摘要
自溶素是由细菌产生的可以降解细菌细胞壁的肽聚糖水解酶,参与细菌的分裂、细胞壁更新、细菌自溶等生理过程。自溶素也是细菌的重要毒力因子之一,参与细菌的黏附与侵袭,与细菌的致病性密切相关。本文对单核细胞增生性李斯特菌的胞壁水解酶p60、酰胺酶Ami、自溶素IspC、自溶素Auto与胞壁水解酶MurA等自溶素的蛋白结构、生理功能及致病性进行了简要介绍。
Autolysin is a kind of peptidoglycan hydrolase produced by the bacteriumb and able to degrade its own cell wall. This enzyme is involved in numerous cellular processes including cell division, cell-wall turnover and bacterial lysates. Autolysin is closely associated with pathogenicity, which participated in host cell adhesion and invasion. The protein structure, physiological function and pathogenicity of autolysins in Listeria monocytogenes, such as p60, Ami, IspC, Auto and MurA are reviewed here.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2012年第11期290-293,共4页
Food Science
基金
2007年度高等学校博士学科点专项科研基金项目(20070193062)
