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183例梗塞前心绞痛发作对急性心肌梗塞缺血预适应分析 被引量:1

Analysis of the Effect of 183 Angina Attack before Infarction on AMI Ischemic Preconditioning
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摘要 目的 :评价急性心肌梗塞 (AMI)前心绞痛发作对 AMI预后的影响。方法 :对梗塞前一周内心绞痛发作的 AMI 183例与梗塞前无心绞痛发作的 AMI 136例的梗塞面积 ,近期并发症及住院病死率进行比较分析。结果 :有心绞痛发作组梗塞面积较小 (P<0 .0 5 ) ,梗塞后一周内严重心律失常 ,急性肺水肿 ,心源性休克等心血管事件及住院病死率均低于梗塞前无心绞痛发作组 (P<0 .0 5 )。结论 :梗塞前心绞痛发作对心肌产生的缺血预适应有明确的心肌保护作用。 Objective:To evaluate the effect of angina pectoris attack before infarction on the prognosis of acute myocardial infarction(AMI).Methods:The 183 cases of AMI with angina attack within a week before infarction and the 136 cases of AMI without angina attack were compared with each other and analyzed in terms of the infarct size,complication in short term and hospita lization mortality.Results:The infarct size of the group with angina attack is significantly smaller than that of the group without angina attack ( P <0 05).The angiocardiopathy such as severe arrhythmia,acute pulmonary edema and cardiac shock,etc.Within a week after infarction and the hospitalization mortality of the group with angina attack were all significantly lower than that of the group without angina attack( P <0 05).Conclusion:The angina attack before infarction can produce the ischemic preconditioning on myocardium that provides myocardium with definite protection.
出处 《中国慢性病预防与控制》 CAS 2000年第3期122-123,共2页 Chinese Journal of Prevention and Control of Chronic Diseases
关键词 梗塞前心绞痛 急性心肌梗塞 缺血预适应 Angina pectoris before infarction Acute myocardial infarction Ischemia preconditioning
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  • 1Jennifer M.Hahn,Kevin L.McFarland,Kelly A.Combs,Dorothy M.Supp.Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1[J].Burns & Trauma,2016,4(3):199-215. 被引量:19
  • 2Yilmaz M,Christofori G.EMT,the cytoskeleton,and cancer cell invasion.Cancer Metastasis Rev,2009,28(1-2):15-33.
  • 3Voulqari A,Pintzas A.Epithelial-mesenchymal transition in cancer metastasis:Mechanisms,markers,and strategies to overcome drug resistance in the clinic.Biochim Biophys Acta,2009,21:1-16.
  • 4Nakajima S,Doi R,Toyoda E,et al.N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma.Clin Cancer Res,2004,10(12 Pt1):4125-4133.
  • 5Zavadil J,Bottinger EP.TGF-beta and epithelial-to -mesenchymal transitions.Oncogene,2005,24(37):5764-5774.
  • 6Bakin AV,Tomlinson AK,Bhowmick NA,et al.Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.J Biol Chem,2000,275(47):36803-36810.
  • 7Larue L,Bellacosa A.Epithelial-mesenchymal transition in development and cancer:role of phosphatidylinositol 3'Kinase/Akt pathways.Oncogene,2005,24(50):7443-7454.
  • 8Shook D,Keller R.Mechanisms,mechanics and function of epithelial-mesenchymal transitions in early development.Mech Dev,2003,120(11):1351-1383.
  • 9Cano A,Perez-Moreno MA,Rodrigo I,et al.The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.Nat Cell Biol,2000,2(2):76-83.
  • 10Rahimi RA,Leof EB.TGF-beta signaling:a tale of two responses.J Cell Biochem,2007,102(3):593-608.

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  • 1Schoemaker RG,Van Heijningen CL.Bradykinin mediates cardiac preconditioning at a distance. Am J Physiol Heart Circ Physiol,2000,278(5):H1571-H1576.
  • 2Kloner RA,Shook KT. Previous angina alters in-hospital outcome in TIMI 4.A clinical orrelate to preconditioning?Circulation,1995,91(1):37-45.
  • 3Andreotti F,Pasceri V,Hackett DR,et al.Preinfarction angina as a predictor of more rapid coronary thrombolysis in patients with acute myocardial infarction. N Eng J Med,1996,334(1):7-12.
  • 4Gho BC,Schoemaker RG,Van den Doel MA,et al.Myocardial protection by brief ischemia in noncardiac tissue.Circulation,1996,94(9):2193-2200.
  • 5Baxter GF,Marber MS,Patel VC,et al.Adenosine receptor involved in a delayed phase of myocardial protection 24h after ischemic preconditioning. Circulation,1994,190(6):2993-3000.

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