摘要
目的 观察不同钙摄入量对大鼠氟牙症发生的影响。方法 分别用含低钙、中钙 (即标准钙 )、高钙量的饲料喂养大鼠并使其摄取 0 1mol/LNaF水 ,同时设对照组。 2个月后处死动物 ,分别用氟离子电极、显微放射照相、扫描电子显微镜检测各组动物上中切牙釉质平均氟含量及矿化程度和结构。结果 随摄入钙量的增加 ,大鼠上中切牙釉质中的氟含量减少 (P <0 0 1) ,釉质平均吸光度值减低 (P <0 0 1) ,釉质矿化程度增加。结论 牙齿发育期摄钙量越多 ,牙齿氟中毒程度越轻 ;补钙是预防氟中毒 ,提高硬组织矿化程度的有效手段。
Objective To study the effects caused by uptake of different levels of calcium to dental fluorosis in rats. Methods Weanling rats were raised on water containing 0 1 mol/L fluoride and food containing low, normal and high levels of calcium for 2 months The concentration of fluoride in enamel was analysed by F ion selective electrode The microradiographic examination and light density analysis were performed The enamel structure was examined under SEM Results The more calcium was ingested, the lower level of fluoride amount in enamel was observed( P <0 01) With increasing food calcium ingestion, the light density value was decreasing, and the level of enamel mineralization was increasing( P <0 01) Conclusions With increasing food calcium ingestion during the development of teeth , the level of dental fluorosis is decreasing The calcium supply is effective in protection from fluoride toxicity to a certain extent
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2000年第1期47-49,I005,共4页
Chinese Journal of Stomatology
基金
北京市自然科学基金资助项目
关键词
钙
动物实验
氟牙症
电子显微镜
Calcium
Microscopy,electron,scanning transmission
Animals,laboratory
