摘要
阿尔茨海默病(AD)是一种病因不明的神经系统退行性疾病。介绍了目前关于AD发病机制常见的几种学说,并从单味中药、复方的角度总结中医药对AD的干预作用,包括调节神经递质、减轻炎症与免疫反应、减少细胞凋亡、抑制神经纤维缠结等,提出探索AD中医病理与西医病理之间的交叉点,发现两者之间的内在联系,可成为筛选有效治疗AD中药的有效途径。
AD is a progressive neurodegenerative disease of unclear pathogeny. This article discusses the pathogenesis of AD from the role of cholinergic neurons loss, accumulation of b-amyloid peptide and tau protein and immunological and inflammatory reaction. Also, it concludes the effects of single drug and compound prescription on the treatment of AD. The authors point out that finding the interaction and correlation of the pathology from the perspective of western medicine and Chinese medicine might play a key role in treatment of AD. Therefore, traditional Chinese medicine may be a potential therapeutic a- gent for the treatment of AD in future.
出处
《南京中医药大学学报》
CAS
CSCD
北大核心
2012年第4期394-396,共3页
Journal of Nanjing University of Traditional Chinese Medicine
基金
江苏省中医药局中西医结合研究项目(97006)
关键词
阿尔茨海默病
中医药
实验研究
Alzheimer＇s disease
Traditional Chinese Medicine
experiment study
