摘要
以60支健儿清解液装量差异的检测结果为样本,考察了容量法和重量法控制液体制剂装量的效果。结果表明,容量法与重量法测定结果无显著差异;重量法测定结果中有2支超出范围,而容量法测定结果均符合要求。提示采用重量法取代容量法是可行的,且重量法更准确、无污染、低损耗,适于在线控制液体制剂的生产装量。
The volumetric method and gravimetric method for the control of the content uniformity of liquid formulations were investigated with 60 bottles of Jian＇er Qing/ie Ye as samples. The results showed that there was no significant difference between volumetric method and gravimetric method. The results of gravimetric method showed that two samples were out of range, while all samples complied with the requirements according to the results of volumetric method. It suggested that using gravimetric method to replace volumetric method was feasible, and this method was more accurate, no pollution and low loss, which was suitable for online control of the production of liquid formulations.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2012年第8期700-702,共3页
Chinese Journal of Pharmaceuticals
关键词
重量法
容量法
装量差异
控制
gravimetric method
volumetric method
content uniformity
control
