摘要
目的探讨不同检测系统血凝仪之间的可比性,以达到质量控制的效果。方法分别用STA compact和CA-1500血凝仪测定质控、100份比对样本(浓度覆盖生物参考区间),然后对测定结果进行分析、比较,以美国临床医学检验部门修正法规(CLIA'88)允许总误差的1/2及相关性比较(r>0.975)为判断标准,观察2台仪器的可比性、相关性。结果 STA compact和CA-1500血凝仪在测定无黄疸和脂血的标本时国际标准化比值(INR)、低值纤维蛋白原(Fbg)结果一致,相对偏差在允许范围内,相关性较好(r>0.975),而测定活化部分凝血活酶时间(APTT)时相关性尚可,但相对偏差不在允许范围内。在测定黄疸或(和)脂血的标本时INR、APTT、Fbg时结果均不一致,相对偏差不在允许范围内,相关性不好(r<0.975)。结论通过比对可以反应不同检测系统血凝仪结果之间的可比性、相关性及差异。
Objective To investigate the comparability of different detection system blood coagulation analyzers, in order to achieve the efficiency of quality control. Methods With STA compact and CA-1500 blood coagulation analyzers, the quality control material and 100 comparison blood samples （concentration covered biology reference interval） were determined. The measured results were analyzed and compared according to American Clinical Laboratory Improvement Amendment 88（ CLIA＇88 ） allowable total error 1/2 comparison and correlation （r 〉 0. 975 ） as judgment standard. The instrument comparability and correlation were observed. Results When STA compact and CA-1500 blood coagulation analyzers measuring samples without icterus and lipaemia, the results of international normalized ratio （INR） and low-value fibrinogen （Fbg） were consistent. The relative deviation was within allowance range, and the correlation was good （r 〉 0.975）. The result of activated patial thromboplastin time （AFFF） correlation was fair , but the relative deviation was not allowed. The results of INR, APTI＂ and Fbg was inconsistent when the samples was icterus or （and） lipaemia, and the relative deviation was not allowed and the correlation was bad （ r 〈 0. 975）. Conclusions The comparability, correlation and differences can be reflected by comparing the results of different detection system blood coagulation analyzers.
出处
《检验医学》
CAS
2012年第7期527-530,共4页
Laboratory Medicine
关键词
检测系统
国际标准化比值
活化部分凝血活酶时间
纤维蛋白原
相关性
Detection system
International normalized ratio
Activated patial thromboplastin time
Fibrinogen
Correlation
