摘要
目的:探讨磷酸二酯酶5在人前列腺移行带组织中的表达与分布。方法:应用免疫组化SP法,选择前列腺增生患者34例,检测PDE5表达及分布。结果:34例标本中PDE5均呈阳性表达。PDE5在前列腺移行带的腺组织上皮普遍呈中等表达,间质部分弱表达。结论:PDE5在人增生前列腺组织中分布,但分布不均,表明不同PDE5可能行使不同的功能。
Objective： To investigate the Expression and Distribution of Phosphodiesterase 5 （PDE5） in the transitional zone of Benign Prostatic Hyperplasia. Methods： The immunohistochemical SP method was used to detect the expression ＇of PDE5 in the transi- tional zone of Benign Prostatic Hyperplasia. Results： All sections were immunopositive for PDE5. The immnuointensity of PDE 5 was relatively moderate in the epithelium of glandular structures. In contrast, PDE5 showed immunoactivity in the fibromuscular stroma but its immnuointensity was faint. Conclusion： PDE5 is widely distributed in the transitional zone of Benign Prostatic Hyperplasia, but the distri- bution is not even, indicating that different PDE5 may execute the different functions.
出处
《现代生物医学进展》
CAS
2012年第18期3538-3540,共3页
Progress in Modern Biomedicine
基金
浦东新区科技发展基金创新资金(PKJ2009-Y-29)
关键词
磷酸二酯酶5
前列腺增生
免疫组化
Phosphodiesterase 5
Benign Prostatic Hyperplasia
Immunohistochemistry
