期刊文献+

糖基化修饰牛乳清蛋白过敏原性研究进展 被引量:7

Research Advances in Allergenrity of Glycosylated Whey Protein
下载PDF
导出
摘要 牛乳含有丰富的营养物质,是除母乳外婴儿最理想的食品来源。但是,部分婴儿对牛乳会产生过敏反应。通过美拉德反应对乳清蛋白进行糖基化改性是一种比较新的方法,但已经成为食品中研究的热点。本文对牛乳中主要过敏原的结构特征、致敏性、表位等进行阐述,详细地介绍乳清蛋白中α-乳白蛋白和β-乳球蛋白糖基化改性的国内外研究进展。糖基化法作为降低乳清蛋白致敏性的方法之一,能较好地保持其原有结构和功能特性。 Bovine milk is nutritious in multiple aspects. It has become the most suitable food source for infants. However, many infants are allergic to bovine milk. Maillard reaction provides a novel method for glacosylation modifications of whey proteins, and has gained extensive attention in the food field. In this paper, the structural characteristics and allergenicity of major milk allergens are summarized. Glycosylafion modifications of α-lactalbumin and β-lactoglobulin are also reviewed. Meanwhile, the immunogenicity of whey protein can be reduced by conjugation with saccharides, without destroying its molecular structure and functions.
出处 《食品科学》 EI CAS CSCD 北大核心 2012年第13期334-338,共5页 Food Science
基金 黑龙江省教育厅科学技术研究项目(11551062 1155065)
关键词 Α-乳白蛋白 Β-乳球蛋白 过敏原性 糖基化 α-lactalbumin β-lactoglobulin antigenicity glycosylation
  • 相关文献

参考文献36

  • 1POURPAK Z, MOTSAFAIE A, HASAN Z, et al. A laboratory method for purification of major cows milk allergens[J]. Journal of Irnmunoassay & Immunochemistry, 2004, 25(4): 385-397.
  • 2KLEBER N, MAIER S, HINRICHS J. Antigenic response of bovine β-lactoglobulin by ultra-high pressure treatment and temperature[J]. Inno- vative Food Science & Emerging Technologies, 2007, 8(1): 39-45.
  • 3GUADIX A, CAMACHO F, GUADIX E M. Production of whey protein hydrolysates with reduced aUergenicity in a stable membrane reactor[J]. Journal of Food Engineering, 2006, 72(4): 398-405.
  • 4KLEBER N, WEYRICH U, HINRICHIS J. Screening for lactic acid bacteria with potential to reduce antigenic response of β-lactoglobulin in bovine skin milk and sweet whey[J]. Innovative Food Science & Emerging Technologies, 2006, 7(3): 233-238.
  • 5BU Guanhao, LU Yongkang, ZHENG Zhe, et al. Effect of heat treatment on the antigenicity of bovine β-lactalbumin and B-lactoglobulin in whey protein isolate[J]. Food and Agricultural Immunology, 2009, 20 (3): 195-206.
  • 6WROBLEWSKA B, KARAMAC M, AMAROWlCA R, et al. Immu- noreactive properties of peptide fractions of cow whey milk proteins after enzymatic hydrolysis[J]. International Journal of Food Science & Technology, 2004, 39(8): 839-850.
  • 7DAVIS P J, SMALES C M, JAMES D C. How can thermal processing modify the antigenicity of proteins?[J]. Allergy, 2001, 56(Supp167): 56- 60.
  • 8KOBAYASHI K, HIRANO A, OHTA A, et al. Reduced immunogenicity of β-lactoglobulin by conjugation with carboxymethyl dextran differing in molecular weight[J]. Journal of Agricultural and Food Chemistry, 2001, 49(2): 823-831.
  • 9ENA J M, van BERESTEIN E C H, ROBBEN A J P M, et al. Whey protein antigenicity reduction by fungal proteinases and a pepsin/pancre- atic combination[J]. Journal of Food Science, 1995, 60(1): 104-116.
  • 10周永生,周文娟.美拉德反应及其对食品加工过程的影响[J].安徽农业科学,2010,38(27):15092-15095. 被引量:22

二级参考文献83

共引文献42

同被引文献105

引证文献7

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部