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中西医治疗方案对364例轻中度支气管哮喘急性发作患者肺功能的影响 被引量:24

Effect of Combo Therapy of Chinese and Western Medicine on the Lung Function in 364 Mild to Moderate Bronchial Asthma Patients with Acute Exacerbation
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摘要 目的初步评价中医辨证治疗、中医辨证治疗加穴位贴敷、西药常规治疗对支气管哮喘(哮喘)轻中度发作患者肺功能指标中用力肺活量(FVC)、一秒用力呼气容积(FEV1)、一秒率(FEV1/FVC)、峰值流速(PEF)的影响。方法将364例轻中度发作期哮喘患者随机分为3组,辨证治疗组辨证给予口服中药颗粒剂,综合治疗组在辨证治疗组基础上加用中药穴位贴敷,西药组给予口服舒弗美,疗程均为10天。观察患者治疗前后肺功能指标FVC、FEV1、FEV1/FVC、PEF。结果辨证治疗组治疗前后FEV1/FVC、FVC、FEV1、PEF比较差异均有统计学意义(P<0.05)。综合治疗组治疗前后FEV1/FVC、PEF比较差异有统计学意义(P<0.05)。西药组治疗前后FVC、FEV1/FVC、PEF比较差异均有统计学意义(P<0.05)。治疗后各组肺功能指标FVC、FEV1、FEV1/FVC、PEF组间比较差异无统计学意义(P>0.05)。结论中药辨证治疗能够有效改善支气管哮喘患者肺功能FEV1/FVC、FVC、FEV1、PEF,达到控制哮喘发作的目的,中医辨证治疗加穴位贴敷,在改善肺功能指标上疗效较辨证治疗及西药常规治疗稍差。 Objective To observe the effect of Chinese medication according to syndrome identification, Chinese medication according to syndrome identification combined with acupoint application and conventional western medicine treatment on forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC and peak expiratory flow (PEF) in mild to moderate bronchial asthma patients with acute exacerbation. Methods Totally 364 mild to moderate bronchial asthma patients with acute exacerbation were randomized into 3 groups. The Chinese medication group was given oral Chinese medicine gran- ules and the combo therapy group was added acupoint application. The western medication group was given Theophylline oral- ly. The treatment course lasted for 10 days. FVC, FEV1 , FEV1/FVC and PEF were observed before and after treatment. Re- sults There were significant differences in FEV1/FVC, FVC, FEV1 and PEF between before and after treatment in the Chi- nese medication group (P〈0.05). There was significant difference in FEV1/FVC and PEF between before and after treatment in the combo therapy group (P〈0.05). There were significant differences in FEV1/FVC, FVC and PEF between before and after treatment in the western medication group (P〈0.05). There was no significant difference between groups (P〈0.05). Conclusion Chinese medication according to syndrome identification could control asthma through improving FEV1/FVC, FVC, FEV1 and PEF obviously. The effect of Chinese medication according to syndrome identification combined with acupoint application in improving pulmonary function indicators is poorer than those of Chinese medication according to syndrome identi- fication and western medication.
出处 《中医杂志》 CSCD 北大核心 2012年第15期1291-1293,共3页 Journal of Traditional Chinese Medicine
基金 国家科技支撑计划资助项目(2007BAI20B081)
关键词 支气管哮喘 辨证治疗 穴位贴敷 肺功能 bronchial asthma syndrome identification and treatment administration acupoint application lung function
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