摘要
目的观察补肾益智汤治疗老年血管性痴呆(肾虚髓减证)患者的临床疗效。方法将50例患者随机分为两组,每组各25例,治疗组采用补肾益智汤(组成:熟地、龟板、山药、黄精、山茱萸、茯苓、人参、丹皮、泽泻、牛脊髓)治疗;对照组采用甲磺酸双氢麦角碱片治疗。比较治疗2个月后治疗组与对照组Berg平衡量表积分的改善情况和脑电地形图的有效率。结果治疗2个月后,治疗组与对照组Berg平衡量表积分均有提高(P<0.05),两组Berg平衡量表积分比较差异有统计学意义(P<0.05);治疗组对脑电地形图有效率为68%,对照组对脑电地形图有效率为28%,两组对脑电地形图有效率比较,差异有统计学意义(P<0.01)。治疗组疗效明显优于对照组。结论补肾益智汤治疗老年血管性痴呆肾虚髓减证有较好效果,值得临床推广应用。
Objective To observe the clinical efficacy of bushen yizhi decoction for the patients with senile vascular dementia（pattern/syndrome of kidney deficiency and marrow declining）.Methods 50 cases were randomized into two groups,25 cases in each one.In a treatment group,bushen yizhi decoction（ingredients：radix rehmannia preparata,carapax et plastrum testudinis,disoscoprea opposita,rhizome polygonati,cornus officinalis,poria cocos,radix ginseng,cortex moutan,rhizome alismatis,cattle spinal cord）was prescribed.In a control group,co-dergocrine mesyiate tablets were prescribed.At the end of 2-month treatment,the improvements in Berg balance scale score and the effective rate of brain electric activity mapping（BEAM）were compared between the treatment group and the control group.Results At the end of 2-month treatment,the score of Berg balance scale was improved in both the treatment group and the control group（P〈0.05）.The difference in the improvement of Berg balance scale score was significant statistically in comparison between two groups（P〈0.05）.BEAM effective rate was 68% in the treatment group and was 28% in the control group,presenting the statistical significant difference（P〈0.01）.The efficacy in the treatment group was superior apparently to that in the control group.Conclusion Bushen yizhi decoction achieves the better effect on senile vascular dementia（pattern/syndrome of kidney deficiency and marrow declining）and deserves to be promoted in clinical application.
出处
《世界中西医结合杂志》
2012年第7期594-595,598,共3页
World Journal of Integrated Traditional and Western Medicine
基金
太原市民生科技发展计划项目(No.2010100342)
关键词
血管性痴呆
肾虚髓减
补肾益智汤
Vascular Dementia； Kidney Deficiency and Marrow Declining； Bushen Yizhi Decoction
