摘要
目的探讨系统性红斑狼疮治疗过程中并发带状疱疹的治疗方法,以提高治愈率。方法选取50例并发带状疱疹病毒感染的系统性红斑狼疮患者,随机分为两组,所有患者均采用更昔洛韦0.25g静脉滴注q12h及TDP灯局部辅助治疗,观察组同时予以阿昔洛韦粉针剂0.25g加生理盐水20mL局部湿敷后局部照射,每天2次,对照组同时局部涂擦阿昔洛韦软膏,分析比较两组患者的治疗效果。结果观察组与对照组在治疗时间、疗效、预后等方面差异有统计学意义(P<0.05)。结论系统性红斑狼疮并带状疱疹病毒感染患者及时运用全身及局部抗病毒治疗,配合TDP灯照射治疗,效果较好,阿昔洛韦粉针剂运用于局部抗病毒治疗,疗效好,较为安全,值得临床借鉴使用。
Objective To discuss the treatment method of systemic lupus erythematosus patients complicated with herpes zoster treatment and improve its cure rate.Methods 50 cases of systemic lupus erythematosus with herpes zoster virus infection were selected in this study.They were randomly divided into two groups. All the patients were injected with 0.25g of ganciclovir intravenous for ql2h and treated by TDP lamp. Observation group was in part treated by wet dressing with 0.25g acyclovir powder and 20ml saline wet dressing, then exposed to TDP lamp for two times everyday. For the control group, the patients were rubbed with inunction acyclovir ointment in the affected parts. Finally, the therapeutic？effect in the two groups was analysized and compared. Results There were significant differences（P〈0.05）at the cure time, therapeutic effect and prognosis between the observation group and the control group. Conclusion Antiviral therapy for partial or the whole body in time and TDP irradiation has a good therapeutic effect for the patients of systemic lupus erythematosus complicated with herpes zoster virus infection. Acyclovir injection powder, used for partial antiviral therapy, not only has good？curative？effect for patients, but also is？safe for patients. Therefore, it is worthy of clinical use.
出处
《中外医疗》
2012年第20期15-16,共2页
China & Foreign Medical Treatment
