摘要
目的探讨心力衰竭患者治疗前后心肌酶、肌钙蛋白T(cTnT)、C反应蛋白(CRP)水平的变化,为临床诊断与治疗提供参考。方法选择心力衰竭患者60例(治疗组)采用联合用药治疗,治疗前后检测CRP、cTnT、肌酸激酶同工酶(CK-MB)的变化。同期选择体检健康者60例作为对照组,同期检测上述指标。结果治疗组患者治疗后CRP水平恢复到了对照组基准值的水平。治疗后cTnT与CK-MB水平较治疗前明显改善(P<0.05),但仍然明显高于对照组基准值水平(P<0.05)。结论检测心力衰竭患者的CRP、cTnT、CK-MB水平有助于动态评价患者的病情变化及判断临床治疗效果。
Objective To explore the changes of cardiac enzymes,troponin T,C-reactive protein before and after treatment of heart failure（HF） to provide reference for clinical diagnosis and treatment.Methods Sixty HF patients（treatment group） were given combination therapy,and the changes of CRP,CK-MB,cTnT determined before and after treatment.Sixty healthy subjects were enrolled as control group.Results After treatment,the CPR level of treatment group recovered to fiducial value of control group.The levels of cTnT,CK-MB increased significantly as compared with pre-treatment（P〈0.05）,but still higher than fiducial value of control group（P〉0.05）.Conclusion Determination of CRP,cTnT,CK-MB levels helps to evaluate dynamically patients′ condition and clinical therapeutic effect in HF patients.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第20期2338-2339,共2页
Chinese General Practice
