摘要
目的了解天津市弥漫性间质性肺疾病(DILD)住院患者的构成比、临床特征及诊治中存在的问题。方法收集2003—2009年天津市10家综合医院收治住院的DILD病例资料,统计分析DILD住院患者占呼吸内科、全院住院患者的构成比,以及各临床表现、肺功能、血气分析、病理学等检查项目结果。结果天津地区DILD住院患者男女比例约为1.32:1,平均年龄为(69.28±12.09)岁。2003年DILD住院患者占呼吸科住院人数的4.52‰,占全院住院人数的0.31‰,2009年分别为39.5‰和1.51‰。影像学以网格状改变为主的占43.2%,以毛玻璃改变为主的占25.6%,伴有蜂窝样改变的占11.4%。26.7%的患者有肺功能检查资料,其中10.3%的患者行弥散功能检查。大多数患者存在低氧血症,氧合指数为(281.0±98.3)mm Hg。4.0%的患者行支气管肺泡灌洗检查,3.5%的DILD患者有病理学资料。结论 DILD住院患者占呼吸科和医院住院患者构成比均呈上升趋势。确诊需要有经验的临床、放射和病理科医生共同参与。需提高对肺功能、支气管肺泡灌洗及肺活检的认识。
Objective To investigate the constituent ratio and clinical features of diffuse interstitial lung disease（DILD） in Tianjin city,and to identify the questions of diagnosis and management of DILD.Methods Data was collected from inpatients with DILD in ten general hospitals in Tianjin from 2003 to 2009 for statistical analysis of the constituent ratios of DILD in the respiratory department and in the whole hospital,clinical manifestations,lung function,blood gas and pathological examination.Results The average age of DILD patients was（69.28±12.09） years with a ratio of male to female of 1.32：1.The constituent ratio of DILD was 4.52‰ in respiratory department and 0.31‰ in hospital in 2003;and increased to 39.5‰ and 1.51‰ respectively in 2009.The imaging changes were basically graticule change accounting for 43.2% and ground glass change accounting for 25.6%,or accompanied change of honeycombing accounting for 11.4%.There were 26.7% of the patients who underwent lung function test and 10.3% of the patients underwent diffusion function test.Most patients had hypoxemia,with oxygenation index of（281.0±98.3） mm Hg;and there were 4.0% of the patients underwent bronchoalveolar lavage,and 3.5% had pathologic data.Conclusion The constituent ratio of DILD inpatients shows an increasing trend.A definite diagnosis of DILD needs cooperation of experienced clinical physicians,radiologists and pathologists.It is necessary to raise the cognition of lung function bronchoalveolar lavage and lung biopsy.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第22期2521-2524,共4页
Chinese General Practice
关键词
肺疾病
间质性
流行病学
多中心研究
Lung disease
interstitial
Epidemiology
A multi-center study
