摘要
目的:探讨依达拉奉联合氯吡格雷治疗急性脑梗死的临床疗效。方法:随机选取在笔者所在医院治疗的急性脑梗死患者80例,分为观察组和对照组。对照组(40例)单独使用氯吡格雷治疗;观察组(40例)使用依达拉奉和氯吡格雷联合治疗。对比两组临床治疗效果和治疗前后神经功能缺损评分。结果:治疗2周、3周、1个后时观察组神经功能评分分别为(14.24±6.51)分、(12.32±5.12)分和(10.35±6.29)分,明显低于对照组(P<0.05)。观察组治疗总有效率为95.0%,高于对照组的77.5%,差异有统计学意义(P<0.05)。结论:依达拉奉联合氯吡格雷治疗急性脑梗死可有效改善预后,安全有效,不良反应少,值得临床推广。
Objective ：To explore the clinical effect of of clopidogrel combined with edaravone in treatment of acute cerebral infarction.Method ：Randomly selected 80 cases of acute cerebral infarction patients treated in author＇ s hospital and divided into the observation group and control group.The control group （n=40） was treated with clopidogrel alone ; The observation group （n=40） was treated with clopidogrel and edaravone.Compared the two groups occurrence of clinical treatment effect and nervous function defect score before and after treatment.Result ：After treatment for 2weeks, 3 weeks, 1 months in observation group, the neurological function score were （14.24±6.51）, （12.32 ±5.12） and （10.35 ± 6.29）, was significantly lower than that of control group （P〈0.05）. Observation of treatment group total effective rate of 95%, higher than that of control greup77.5%, there was significant difference （P〈0.05）.Conclusion ：Edaravone combined with clopidogrel in the treatment of acute cerebral infarction can effectively improve the prognosis, safe and effective, with few adverse reactions, worthy of clinical application.
出处
《中国医学创新》
CAS
2012年第22期122-123,共2页
Medical Innovation of China
关键词
急性脑梗死
依达拉奉
氯吡格雷
临床疗效
Acute cerebral infarction
Edaravone
Clopidogrel
Clinical effect
