摘要
目的评价支气管内超声引导针吸活检术（EBUS—TBNA）对肺癌患者应用正电子发射计算机体层摄影（PET—CT）诊断纵隔阳性淋巴结的评估。方法回顾性分析2008年7月至2010年8月间接受PET—CT和EBUS—TBNA检查的126例肺癌患者的临床相关资料和穿刺活检的结果。结果126例患者成功穿刺185组淋巴结。PET-CT检查结果显示，肺癌并纵隔淋巴结代谢增高，异常浓聚，标准摄取值（SUV）〉2．5。EBUS—TBNA检查可见纵隔多组淋巴结，大小约6～23mm，平均13．6mm。对PET—CT诊断为纵隔阳性的淋巴结再行EBUS—TBNA，EBUS—TBNA诊断的准确性为95．7％，灵敏度为95．7％，特异度为100％。结论EBUS-TBNA作为纵隔淋巴结病理诊断的一种检查方法，其创伤性小，准确性高，对肺癌患者经PET—CT检查为纵隔阳性淋巴结诊断的评估是安全、可行和有效的。
Objective To evaluate the clinical value of endobronchial ultrasound-transbronchial needle aspiration （EBUS-TBNA） biopsy for diagnosis of PET-CT positive mediastinal lymph nodes. Methods One hundred and twenty-six patients with lung cancer undergoing both PET-CT scanning and EBUS-TBNA biopsy in the First Affiliated Hospital of Guanzhou Medical College from July 2008 to August 2010 were included in this study. There were 89 male and 37 female patients with a mean age of 56.3 years （range 34 to 81 years）. 18FDG-PET was considered positive in mediastinal nodes if the PET-CT reported hypermetabolic activity consistent with malignant disease （ standardized uptake value 〉 2.5 ）. All of the patients were clinically followed up. Results Among the 126 patients, 185 stations of lymph nodes were punctured. The mean diameter of the nodes was 13.6 mm and the range was 6-23 mm. There were no procedural complications. The diagnostic accuracy, sensitivity, and specificity of EBUS-TBNA were 95.7%, 95.7%, and 100%, respectively. Conclusions EBUS-TBNA is a minimally invasive, highly effective and accurate, practical and safe procedure for diagnosis of PET-CT positive mediastinal lymph nodes.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2012年第8期613-615,共3页
Chinese Journal of Oncology
基金
广东省科技厅一般项目基金（030801357）
关键词
肺肿瘤
支气管内超声引导针吸活检术
正电子发射计算机体层摄影
纵隔
淋巴结
Lung neoplasms
Endobronchial uhrasound-transbronchial needle aspiration
Positron emission tomography-computed tomography
Mediastinum
Lymph node
