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舟山地区2008-2011年手足口病流行趋势及病原分析 被引量:2

Epidemiological and etiolog characteristics of hand, foot and mouth disease in Zhoushan, 2006-2011
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摘要 目的了解舟山市手足口病疫情流行特征,为制定防控措施提供参考依据。方法采用描述流行病学方法对2008—2011年报告的手足口病病例进行分析。结果2008--2011年舟山市共报告手足口病1831例,重症病例7例,无死亡病例,呈散发状态,未发生暴发疫情,年均发病率为41.10/10万。定海区年均发病率最高(52.11/10万),岱山县最低(26.26/10万)。男性发病高于女性,以散居儿童和幼托儿童为主,集中于0~5岁儿童,占96.18%。发病高峰一般在4—8月,2008年和2009年有2个发病高峰,2010年和2011仅有一个发病高峰。病原学监测结果显示以EV71和其他肠道病毒为主,7例重症病例中,均检测EV71型阳性。结论舟山海岛地区手足口病发生有明显的年龄、性别、职业和季节差异,流行毒株以EV71和其他肠道病毒为主,重症病例流行毒株以EV71为主。 Objective To analyze the epidemiological characteristics of hand, foot and mouth disease(HFMD) in Zhoushan and provide scientific evidence for the prevention and control of the disease. Methods Descriptive epidemiological analysis was conducted on the incidence data of HYMD reported from 2008 to 2011. Results A total of 1831 HFMD cases with 7 severe cases and no dead cases were reported during this period. The average annual incidence was 41.10/100 000. The highest average annual incidence rate was reported in Dinghai district(52.11/100 000) and lowest in Daishan district(26.26/100 000). The case number in males was obviously higher than that in females. Children aged 0-5 years were in high risk. the cases among them accounted for 96.18% of the total. Tne incidence peak occurred between April and August, and two incidence peaks occurred in 2008 and 2009, and one incidence peaks occurred in 2010 and 2011. Etiological surveillance indicated that HFMD cases were mainly caused by EV71 and other intestinal virus infection. Seven severe cases were mainly caused by EVT1. Condusions The incidence of HTMD varies by age, sex, population and season in Zhoushan islands municipality. The epidemic isolates are EV71 and other intestinal virus. The prevalent strain of severe cases is EV71.
出处 《国际流行病学传染病学杂志》 CAS 2012年第4期246-248,共3页 International Journal of Epidemiology and Infectious Disease
关键词 手足口病 流行特征 病原学 Hand, foot and mouth disease Epidemiological characteristics Etiology
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  • 1吴长有,刘杰,杨滨燕,Mario Roedere.人外周血NK细胞亚群、表型和生物学特征[J].中国免疫学杂志,2005,21(7):483-486. 被引量:34
  • 2谭洁,何雅青,杨洪.深圳市2004年手足口病暴发疫情处理及病原学检测[J].实用预防医学,2005,12(6):1345-1346. 被引量:43
  • 3梁艳,邓安梅,仲人前.NK细胞识别和杀伤机制研究进展[J].中国免疫学杂志,2007,23(3):284-287. 被引量:11
  • 4中国疾病预防控制中心.手足口病预防控制指南(2009版)[K].北京,2009.
  • 5中华人民共和国卫生部.手足口病预防控制指南(2009版)[S].2009.
  • 6中华人民共和国卫生部.手足口病预防控制指南(2008年版)[J/OL].http://61.49.18.65/newshtml/21751.hun.
  • 7Schmidt N, Lennette EH,HO HH. An apparently new enterovirus isolated from patients with disease of the central nervous system[J]. J Infect Dis, 1974,129 (3) :304 - 309.
  • 8Ishiko H,Shimada Y, Yonaha M,et al. Molecular diagnosis of human enterovimses by phylogeny - based classification by use of the VP4 sequence[J]. J Infect Dis,2002,185(6) :744-754.
  • 9Wu Y,Yeo A,Phoon MC,et al. The largest outbreak of hand;foot and mouth disease in Singapore in 2008 :The role of enterovirus 71 and coxsaekievirus A strains [ J ]. Int J Infect Dis, 2010,14 ( 12 ) : e1076 - 1081.
  • 10Chang GH, Lin L, Luo Y J, et al. Sequence analysis of six enterovirus 71 strains with different virulences in humans[ J]. Virus Res,2010, 151(1) :66 - 73.

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