摘要
目的回顾性分析神经外科铜绿假单胞菌(PAE)下呼吸道感染医院暴发原因及控制措施,探求引起多药耐药PAE感染可能存在的危险因素。方法对PAE感染患者以流行病学方法进行调查、分析,辅以环境监测及细菌鉴定。结果该次PAE医院感染暴发主要以消毒不严格的螺纹管及雾化管道所致,呼吸机螺纹管及雾化管道PAE检出率为100.0%,患者家属的手PAE检出率为80.0%;由于环境中PAE感染源的持续存在以及抗菌药物长时间、联合应用促进了多药耐药PAE的感染。结论将PAE感染患者统一隔离,并采取严格的消毒措施、加强护理,严格抗菌药物的使用等,有效控制PAE医院感染的再扩大。
OBJECTIVE To evaluate the causes and preventive measures of outbreak of lower respiratory infections caused by Pseudomonas aeruginosa in patients in neurosurgery department, and explore the risk factors for multidrug-resistant P. aeruginosa infections. METHODS The epidemiology of the P. aeruginosa infections was investigated with the complement of environmental monitoring and bacterial identification. RESULTS The P. aeruginosa infection was primarily caused by non-strict sterilization of corrugated tubes or atomized pipes; the detection rate of P. aeruginosa isolates from ventilator threaded pipes and atomized pipes was 100. 0%. The detection rate of P. aeruginosa from the patients＇ family members was 80. 0% the continuously existing of P. aeruginosa infection sources in the environment and the long duration and combined use of antibiotics have promoted the multidrug-resistant P. aeruginosa infections. CONCLUSION The patients with P. aeruginosa infections should be separated, strict disinfection measures should be taken to strengthen the nursing, the antibiotics should be used strictly so as to the effectively control the spread of P. aeruginosa infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第16期3539-3540,共2页
Chinese Journal of Nosocomiology
