摘要
目的探讨前列腺穿刺活检针数对于前列腺癌检出率的差异。方法比较不同PSA水平患者穿刺针数(8针以下穿刺、8～11针穿刺和12针及以上穿刺)对于前列腺癌检出率的影响。结果本组1122例,8针以下穿刺组、8～11针穿刺组和12针及以上穿刺组的前列腺癌检出率分别为59.9%、41.7%、40.7%。将患者按照不同前列腺特异抗原(PSA)水平以及直肠指诊(DRE)结果进行分组后发现,随PSA升高前列腺癌检出率增加,相同PSA水平时DRE阳性患者前列腺癌检出率高于DRE阴性患者。PSA(4～9.9)μg/L且DRE阴性的患者中,不同穿刺针数组的前列腺癌检出率分别是10.0%、24.4%和30.3%。PSA(10～19.9)μg/L且DRE阴性的患者中三组前列腺癌检出率分别是0%、26.1%和42.9%。结论前列腺癌的检出率与患者PSA水平及DRE结果相关,12针以上的穿刺活检在PSA4～20μg/L且直肠指诊阴性的患者中显著提高前列腺癌检出率。
Objective To evaluate the influence of biopsy cores on the detection of prostate cancer. Methods From June 1996 to September 2010 a total of 1122 patients accepted transrectal ultrasound guided prostate biopsies in Beijing Hospital. We retrospectively analyzed prostate cancer detection rate in groups with different biopsy cores （less than 8 cores, 8 - 11 cores and more than 12 cores）. Results The total positive biopsy rates （PBR） of the three groups are 59.9% , 41.7% and 40.7% respectively. The prostate cancer detection rate correlates with the prostate- specific antigen （PSA） level and digital rectal examination （DRE） results. In PSA 4 - 9.9μg/L and DRE negative subgroups, the PBR of the three different biopsy-core groups are 10.0% ,24.4% and 30.3% , respectively. In PSA 10 - 19.9μg/L and DRE negative subgroups the outcomes are 0% ,26.1% and 42.9%. Conclusion The prostate cancer detection rate correlates with PSA level and DRE resuh. Increasing biopsy cores may increase the detection rate of prostate cancer in PSA 4 -20μg/L and DRE negative subgroups.
出处
《中国医刊》
CAS
2012年第8期35-36,共2页
Chinese Journal of Medicine
