摘要
目的:观察肾衰系列方配合针刺治疗慢性肾脏病(CKD4期)的疗效;制订体现中医特色的治疗方案。方法:采用肾衰系列方配合针刺治疗本病60例,并设对照组,观察两组治疗前后症状变化;肝、肾功能、24h尿蛋白定量、尿微量蛋白、血红蛋白、甘油三酯、胆固醇、高密度脂蛋白及血液流变学的数据变化以评定疗效。结果:治疗组对慢性肾炎疗效显著,总有效率为93.3%,优于对照组46.7%,两组比较有显著性差异(P<0.05);且治疗组能显著改善临床症状;提高肌酐清除率;降低肌酐、尿素氮、24h尿蛋白定量、尿微量蛋白,升高血红蛋白、血清白蛋白及总蛋白同时改善血流变及胆固醇、血脂指标。治疗前后比较,有显著性差异(P<0.05),与对照组比较,有显著性差异(P<0.05)。结论:本方法对慢性肾脏病(CKD4期)疗效满意、安全可靠,值得临床应用。
Objective：To observe the clinical effect of series of prescription and acupuncture on chronic kidney disease in IV stage and to work out the therapy with characteristic of Chinese medicine.Methods：One hundred and twenty patients were randomly divided into two groups：treated group（60 cases）and controlled group（60 cases）.The patients of two groups were received the same basic treatment.Treated group was given treantment with Shenshuai series of prescription and acupuncture;controlled group was given treantment with Niaoduqing granule.The treatment course was eight weeks,there were three courses in two groups.The diversification of symptom in both of two groups before and after treatment was observed.The diversification of the data about liver and kidney function,the proteinuria numbers of 24hours,trace protein,total cholesterol,total riglyceride,high density lipoprotein hemoglobin and hemorheology were observed and compared.Meanwhile we assessed the treating effects.Results：There was evident effect in treated group.The total effective rate was 93.3% in treated group,it was better than that in the controlled group（46.7%）（P0.05）.Meanwhile treated group can not only obviously improve clinical symptoms and enhance glomerular filtration rate but also decline blood urine nitrogen serum dreatinine,the proteinuria numbers of 24hours,trace protein,Total cholesterol,total riglyceride,high density lipoprotein,Hemoglobin,Hemorheology.There was statistical difference not only before and after treatment（P0.05）but also between two groups（P0.05）.Conclusion：Through the results of clinical research we can conclute that Chinese treating therapy can effectively treat patients of chronic kidney disease in IV stage.The treatment effects and safety of Chinese treating therapy are fine.It is worthy of in-depth study and clinical application.
出处
《辽宁中医杂志》
CAS
2012年第8期1563-1567,共5页
Liaoning Journal of Traditional Chinese Medicine
基金
天津市卫生局课题(11009)
关键词
慢性肾脏病(CKD4期)
中医疗法
肾衰系列方剂
针刺
chronic kidney disease in IV stage
treatment with Chinese medicine
Shenshuai series of prescription
acupuncture
