摘要
目的:采用简易疲乏量表中国版(BFI-C)、肺癌症状分级量化表评价中医药治疗对肺癌化疗性疲乏的影响。方法:将67例符合课题纳入标准的肺癌将行化疗患者随机分为治疗组(33例)和对照组(34例),两组患者均按照既定化疗方案施行化疗,治疗组于化疗第1天开始服用健脾益气化痰自拟方加减治疗,对照组未给予其他干预措施。分别在化疗前、化疗第3天(化疗后)和化疗第14天(治疗后)采用BFI-C对所有患者进行评估,同时对两组患者的中医证候评分进行评价,比较两组的评价结果。结果:化疗前,两组患者的综合疲乏程度、综合疲乏影响评分及中医证候积分比较,差异均无统计学意义(P>0.05);化疗后,两组患者的上述评分均显著升高(P<0.01);治疗后,两组患者的上述评分均显著降低(P<0.01),且治疗组的评分较对照组降低更加明显(P<0.01)。结论:①部分因化疗引起的癌性疲乏在一定程度上可自行缓解。②中医药治疗可降低肺癌化疗性疲乏的程度,改善患者的相关症状,提高其生存质量。
Objective： To evaluate the influence of traditional Chinese medical treatment on cancer-related fatigue （CRF） in pulmonary carcinoma patients after chemotherapy by Brief Fatigue Inventory-Chinese Version （ BFI-C ） and Lung Cancer Symptom Scalar Quantization Table. Methods： Sixty-seven lung cancer patients were randomly divided into treatment group （33 cases） and control group （34 cases）. All the patients were treated with chemotherapy, and the treatment group was treated with ＂Spleen-invigoration, Qi-replenishment and Phlegm-elimination Recipe＂ from the 1 st day of chemotherapy. Every patient was evaluated by adopting BFI-C before chemotherapy, three days and fourteen days after chemotherapy, meanwhile the traditional Chinese medical （TCM） syndrome scores of two groups were evaluated and compared. Results： There were no statistical differences on the scores of fatigue severity and fatigue interference and the TCM syndrome scores between two groups before chemotherapy （ P 〉 0.05 ） ; the scores above of two groups obviously increased after chemotherapy （ P 〈 0.01 ） ; the scores above of two groups significantly decreased after treatment （ P 〈 0.01 ） , and the scores of treatment group were lower than those of control group （ P 〈 0.01 ）. Conclusion： （1）CRF caused by chemotherapy can alleviate spontaneously in a certain degree. （2）Traditional Chinese medical treatment can reduce the severity of CRF in lung cancer patients after chemotherapy, improve the correlative symptoms and enhance the quality of life.
出处
《上海中医药大学学报》
CAS
2012年第4期37-40,共4页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30973724)
国家科技重大专项子课题资助项目(2011ZX09302-006-04)
关键词
肺癌
化疗性疲乏
简易疲乏量表(BFI-C)
中医药疗法
Pulmonary carcinoma
cancer-related fatigue （CRF）
Brief Fatigue Inventory-Chinese Version （ BFI-C ）
traditional Chinese medical therapy
