摘要
目的:探讨动态监测血清降钙素原(PCT)对多发伤合并脓毒症的诊断价值。方法:选取我院重症监护室并发脓毒症的多发伤患者21例(Sepsis组)、无并发脓毒症的多发伤患者20例(非Sepsis组),连续检测患者入院第1、3、5、7 d血清中的PCT含量,并测定C反应蛋白和白细胞计数。结果:Sepsis组血清PCT浓度明显高于非Sepsis组(P<0.01);不同程度脓毒症患者间PCT水平有显著差异,随严重程度升高而升高(P<0.01)。结论:血清PCT对多发伤患者合并脓毒症的诊断具有重要价值,且血清PCT水平与脓毒症的严重程度有关,监测其动态变化有助于预后判断。
Objective： To explore the clinical significance of dynamic determination of serum procalcionin（PCT） levels in judgement of sepsis patients after multiple trauma. Methods： 41 patients with multiple trauma were divided into sepsis group（20 cases） and non-sepsis group（20 cases）, the levels of PCT, WBC and C-reactive protein （CRP） of all samples at 1, 3, 5, 7 day were detected and analysed. Results： The level of PCT in sepsis group was significantly higher than non-sepsis group（P〈0.01）. The PCT level was increased with increasing severity of sepsis significantly（P〈0.01）. Conclusion： The alteration of serum PCT level may be used as one of the effective predictors for sepsis patients after multiple trauma and for their prognosis.
出处
《生物技术通讯》
CAS
2012年第4期592-594,共3页
Letters in Biotechnology
