摘要
目的通过多中心、大样本的临床研究，分析儿童一过性意识丧失（transientlossofcon．sciousness，TLOC）的基础疾病谱。方法研究对象为1999年8月至2011年4月在北京、湖南、湖北、上海四地晕厥专科门诊就诊或住院的937例TLOC患儿，对其进行病因学分析。结果937例TLOC患儿中，903例（96．4％）为晕厥患儿，34例（3．6％）为非晕厥患儿。903例晕厥患儿中，213例（23．6％）为血管抑制型血管迷走性晕厥（vasovagalsyncope，VVS），46例（5．1％）为心脏抑制型VVS，112例（12．4％）为混合型VVS，268例（29．7％）为体位性心动过速综合征，22例（2．4％）为直立性低血压，19例（2．1％）为境遇性晕厥，21例（2．3％）为心源性晕厥，202例（22．4％）患儿为不明原因晕厥。结论晕厥是儿童TLOC最常见的原因。在晕厥患儿中，VVS最常见，其次为体位性心动过速综合征。在VVS的3种不同血流动力学类型中，最常见的类型为血管抑制型VVS。
Objective To analyze the spectrum of underlying diseases in children with transient loss of consciousness （TLOC） through a multi-center and large sample clinical research. Methods Nine hundred and thirty-seven children with TLOC who came from Beijing ,Hunan province ,Hubei province and Shanghai of China from Aug 1999 to Apr 2011 were recruited in the present study,and then the spectrum of underlying diseases in children with TLOC was analyzed. Results In 937 children with TLOC, 903 cases （96.4%） were children with syncope,34 cases （3.6 % ） were non-syncope. And in 903 children with syncope, 213 ca- ses （23.6%） had vasovagal syncope （VVS） with vasoinhibitory response,46 cases （5.1% ） had VVS with cardioinhibitory response,ll2 cases （12. 4% ） had VVS with mixed response,268 cases （29. 7% ） had pos- tural tachycardia syndrome,22 cases （2.4%） had orthostatic hypotension, 19 cases （2. 1% ） had situational syncope,21 cases （2. 3% ） had cardiogenic syncope, and 202 cases （22. 4% ） had unexplained syncope. Conclusion In children with TLOC, syncope was the most common underlying disease. And in children with syncope,the most common was VVS, followed by postural tachycardia syndrome. In three different hemody- namic patterns of VVS, the most common pattern was VVS vasoinhibitory pattern.
出处
《中国小儿急救医学》
CAS
2012年第4期360-363,共4页
Chinese Pediatric Emergency Medicine
基金
国家科技支撑计划课题（2012BAI03B03）,北京市科技计划项目（D10100050010059）,首都医学发展基金（2009-1008）
