摘要
目的了解该地区下呼吸道感染铜绿假单胞菌(PAE)对抗菌药物的耐药性,为临床预防医院内感染及合理使用抗菌药物提供科学依据。方法采集2010年10月1日至2011年10月1日下呼吸道感染标本,应用常规方法进行细菌培养、鉴定,并对分离的PAE采用K-B法进行12种临床常用抗菌药物体外药敏试验。结果 PAE对抗感染药物敏感率以头孢他啶(70.75%)、哌拉西林/他唑巴坦(60.85%)最高,其余依次为美罗培南(59.43%)、阿米卡星(58.96%)和哌拉西林(55.66%)等;而耐药率较高者为头孢噻肟、庆大霉素等;总体来看,PAE耐药情况比较严重。结论下呼吸道感染PAE存在单一及多重耐药性,需引起高度重视,医院须加强预防措施,切实降低PAE医院内感染率。
Objective To explore the drug resistance of Pseudomonas aeruginosa（PAE） causing lower respiratory infection, so as to provide scientific basis for controlling nosocomial infection and rational usage of antibiotics. Methods Samples of lower respiratory tract were collected during October 1,20.10 to October 1,2011 and detected for pathogenic bacteria by using routine methods. K-B method was performed for the detection of drug resistance of isolated PAE strains to 12 kinds of commonly used antibiotics. Results The drug resistance rates of PAE stains to Ceftazidime, Piperacillin/Tazobactam, Meropenem, Amikacin, Piperacillin were 70.75%, 60.85%, 59.43%, 58.96% and 55.66%, and to Cefotaxime and Cefotaxime were relatively high. Overall, the drug resistance of PAE might be serious. Conclusion PAE, causing lower respiratory infection, might be with single or multi-- drug resistance, which should be paid for more attention. Preventive measures should be strengthened to reduce nosocomial infection of PAE.
出处
《国际检验医学杂志》
CAS
2012年第10期1219-1220,共2页
International Journal of Laboratory Medicine
关键词
假单胞菌
铜绿
呼吸道感染
交叉感染
抗菌药
抗药性
pseudomonas aeruginosa
respiratory tract infections
cross infection
anti-bacterial agents
drug resistance
