摘要
目的:探讨血浆同型半胱氨酸(Hcy)水平对绝经后骨质疏松的影响。方法:调查200名绝经后妇女,采用双能X线吸收法(DXA)测量骨密度,采用Hcy荧光定量检测试剂盒检测血浆Hcy水平。结果:骨质疏松组血浆Hcy水平明显高于非骨质疏松组,差异具有统计学意义(P<0.05);骨质疏松组血浆Hcy水平与骨密度呈显著负相关(r=-0.16,P<0.05),相对危险度OR为9.214(95%CI=3.28-29.92)。结论:血浆Hcy水平升高是绝经后骨质疏松的独立危险因素。
Objective：To investigate the relationship between postmenopausalosteopomsis and plasma homocysteine （Hcy） level.Methods：200 postmenopausal women were inquired in this study. The bone mineral density （BMD） of the 200 women were detected by DXA, plasma Hcy level were detected by high-performance liquid chromatography-fluorescence detection （HPLC-FD）.Results：The plasma level of women in osteoporosis group was obviously higher than that of non- osteoporosis group （P〈 0.05）. In osteoporosis group, the plasma level had obvious negative correlation with osteoporosis （r=-0.16, P〈 0.05）, the relative risk OR was 9.214 （95%CI=3.28-29.92）.Conclusions：Hyperhomocysteinemia is the independent risk factor for postmenopausalosteoporosis.
出处
《承德医学院学报》
2012年第3期253-255,共3页
Journal of Chengde Medical University
