摘要
目的:调查、分析北京市延庆县医院门诊抗菌药物应用现状、趋势,为临床合理用药和降低医药费用提供参考。方法:采用用药频度(DDDs)分析法,对2011年门诊抗菌药物应用情况进行回顾性统计、分析。结果:总处方数756 698张,使用抗菌药物处方152 303张,使用抗菌药物处方比例为20.13%,抗菌药物金额比例为19.15%(14 680 300.00/76 659 530.00)。使用的抗菌药物中,注射剂所占金额比例为46.20%(6 782 298.60/14 680 300.00),口服剂型为53.80%(7 898 001.40/14 680 300.00);注射剂所占DDDs比例为12.31%(77 934.61/633 100.00),口服剂型为87.69%(555 165.39/633 100.00);注射剂的限定日费用(DDC)为90.03元,口服剂型为14.71元。使用的抗菌药物共12类57个品种102个规格,销售金额和DDDs排序中头孢菌素类、大环内酯类、青霉素类均分别居第1、2、3位,排序比都=1。药物利用指数(DUI)>1的有17个品种17个规格,DUI≤1的有40个品种85个规格。注射用抗菌药物前10位药品销售金额占全部抗菌药物销售金额比例为36.79%(5400 499.00/14 680 300.00),DDDs占总DDDs比例为10.28%(65 052.69/633 100.00);DUI≤1的有7种,DUI>1的有3种。口服抗菌药物DDDs排序前10位药品销售金额占全部抗菌药物销售金额比例为40.12%(5 889 758.18/14 680 300.00),DDDs占总DDDs比例为66.77%(4 226 98.45/633 100.00);DUI≤1的有6种,DUI>1的有4种。结论:我院门诊抗菌药物临床应用总体来说较为合理;但处方比例应降到20%以下,存在世界卫生组织(WHO)推荐的DDD与药品说明书相矛盾、药品说明书与合理用药理论相矛盾的现象。
OBJECTIVE： To investigate and analyze the status quo and tendency of the utilization of antibacterials in the outpatients of Beijing Yanqing County Hospital to offer references for clinical rational medication and reduction of medical expense.METHODS： By using DDDs analysis,the utilization of antibacterials in the outpatients of our hospital in 2011 was analyzed statistically.RESULTS： A total of 756 698 prescriptions were reviewed,with antibacterials prescribed in 152 303（20.13%） and antibiotics represented 19.15%（14 680 300.00/76 659 530.00） in term of consumption sum,which totaled 57 kinds in 12 categories and 102 specifications.In the ratio of the amount the injection is 46.20%（6 782 298.60/14 680 300.00）and oral administration dosage-form is 53.80%（7 898 001.40/14 680 300.00）.In the ratio of DDDs the injection dosage-form is 12.31%（77 934.61/633 100.00） and oral administration dosage-form is 87.69%（555 165.39/633 100.00）.DDC injection dosage-form is 90.03 yuan,and oral administration dosage-form is 14.71 yuan.In terms of consumption sum and DDDs ranked in descending order,cephalosporins,macrolides and penicillins dominated the first 3 places in order,with sequential ratios=1 for all the three.DUI〉1 was noted in 17 kinds（17 specifications） and DUI≤1 in 40 kinds（85 specifications）.Of all the antibacterials used,the top 10 antibiotics for injection represented 36.79%（5 400 499.00/14 680 300.00） in terms of consumption sum and 10.28%（65 052.69/633 100.00） in terms of DDDs,with DUI≤1 in 7 kinds and DUI〉1 in 3 kinds;the top 10 oral antibiotics ranked by DDDs represented 40.12%（5 889 758.18/14 680 300.00） in terms of consumption sum and 66.77%（4 226 98.45/633 100.00） in terms of DDDs,with DUI≤1 in 6 kinds and DUI〉1 in 4.CONCLUSION： The utilization of antibacterials in the outpatients of our hospital was rational on the whole;however,the prescription rate of which should be declined to below 20%;and there is contradiction between the DDD recommended by WHO and that specified in drug package inserts and between the drug package inserts and the rational drug use theory.
出处
《中国医院用药评价与分析》
2012年第7期607-610,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
