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肿瘤坏死因子相关凋亡诱导配体在甲状腺癌治疗中的应用

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摘要 肿瘤坏死因子相关凋亡诱导配体（tumor necrosis factorrelated apoptosis inducing ligand，TRAIL）又称凋亡素2配体（Apo-2L），属于肿瘤坏死因子（TNF）家族一种II型跨膜蛋白。其最显著的生物学特点是具有选择性的细胞毒性作用，
作者 郑桂彬 孟宪瑛 张强 李群
机构地区 吉林大学第一医院甲状腺外科
出处 《中华内分泌外科杂志》 CAS 2012年第4期265-267,共3页 Chinese Journal of Endocrine Surgery
基金 基金项目：吉林省科技厅资助课题（20110136）
关键词 肿瘤坏死因子相关凋亡诱导配体 甲状腺癌 APOPTOSIS 应用 治疗 LIGAND 凋亡素2配体 细胞毒性作用
分类号 R736.1 [医药卫生—肿瘤]
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参考文献26

  • 1Mitsiades N, Poulaki V, Balafouta ST, et al. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-relate apoptosis-inducing ligand [ J ]. Cancer Res, 2000,60( 15 ) :4122-4129.
  • 2Park JW, Wong MG, Lobo M, et al. Modulation of tumor necrosis factor---related apoptosis-inducing ligand-induced apoptosis chemo- therapy in thyroid cancer cell lines [ J ]. Thyroid, 2003,13 ( 12 ) : 1103-1110.
  • 3Maldonado ME, Bousserouel S, Goss F, et al. Implication of NF- KB and p53 in the expression of TRAIL-death receptors and apop- tosis by apple procyanidins in human metastatic SW620 cells [ J ]. Biomedica,2010,30 (4) :577-586.
  • 4De Toni EN, Thieme SE, Herbst A, et al. OPG is regulated by be- ta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer[ J]. Clin Cancer Res,2008,14( 15 ) :4713-4718.
  • 5Pacifico F, Crescenzi E, Mellone S, et al. Nuclear factor- kappa I B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a [ J ]. J Clin Endocrinol Metab, 2010, 95 ( 3 ) : 1421-1430.
  • 6Lannetti A, Pacifico F, Aequaviva R, et al. The neutrophil gelati- nase-associated lipocalin( NGAL), a NF-kappaB-regulated gene, is a survival factor for thyroid neoplastic cells [ J ]. Proe Natl Acad Sci USA ,2008,105 ( 37 ) : 14058-14063.
  • 7Bauerle KT, Schweppe RE, Hauqen BR, et al. Inhibition of nucle- ar factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion[ J]. Mol Cancer,2010,9 : 117.
  • 8Aydin C, Sanlioglu AD, Bisgin A, et al. NF-KB targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL [ J]. BMC Cancer,2010,10:584.
  • 9Liu F, Hu X, Zimmerman M, et al. TNFa cooperates with IFN- to repress Bcl-xL expresstion to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis[ J]. PLoS One,2011,6(1) :e16241.
  • 10Meng Z, Mitsutake N, Nakashima M, et al. Dehydroxymethylep- oxyquinomicin, a novel nuclear factor-kappaB inhibitor, enhances antitumor activity of taxanes in anaplastie thyroid cancer cells [ J ]. Endocrinology,2008,149 ( 11 ) :5357-5365.

二级参考文献22

  • 1张海燕,高大新,刘国良.Survivin基因及其与肿瘤靶向治疗[J].肿瘤防治杂志,2005,12(10):787-790. 被引量：13
  • 2张海燕,高大新,温滨红,刘国良.存活素与血管内皮生长因子在甲状腺癌中的表达及其意义[J].中华内分泌代谢杂志,2005,21(3):244-247. 被引量：11
  • 3Pan G, Ni J, Wei Y F, et al. An antagonist decoy receptor and a death domain-containing receptor for TRAIL [J]. Science, 1997, 277(5327) :815-818.
  • 4Shiraishi T, Yoshida T, Nakata S, et al. Tunicamycin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human prostate cancer cells[J]. Cancer Res, 2005, 65(14) :6364-6370.
  • 5LeBlanc H N, Ashkenazi A. Apo2L/TRAIL and its death and decoyreceptors[J]. Cell Death Differ, 2003, 10(1): 66-75.
  • 6Mitsiades N, Poulaki V, Tseleni-Balafouta S, et al. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand [J]. Cancer Res, 2000, 60(15):4122-4129.
  • 7Wang S H, Mezosi E, Wolf J M, et al. IFNgamma sensitization to TRAIL-induced apoptosis in human thyroid carcinoma ceils by upregulating Bak expression[J]. Oncogene, 2004, 23(4): 928-935.
  • 8Du Zhen-Xian, Wang Hua-Qin, ZhangHai-Yan, et al. Involvement of glyceraldehyde-3 phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cells [J]. Endocrinology,2007,148(9) :4352 -4361.
  • 9Fulda S, Debatin K M. Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the che mopreventive agent resveratrol[J]. Cancer Res, 2004, 64 (1) : 337- 346.
  • 10Griffith T S, Fialkov J M, Scott D L, et al. Induction and regu- lation of tumor necrosis factor-related apoptosis-inducing ligand/ Apo-2 ligan&mediated apoptosis in renal cell carcinoma [J]. Cancer Res, 2002,62(11) : 3093-3099.

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中华内分泌外科杂志
2012年 第4期

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