摘要
目的探讨多发性肌炎(PM)、皮肌炎(DM)患者肌肉MRI表现,评价MRI在PM、DM诊断和疗效评估中的价值。材料与方法对临床资料完整的15例PM和21例DM患者的肌肉MR图像进行回顾分析,所有病例均行治疗前双侧大腿肌肉MRI检查,8例患者进行了治疗后MRI复查。MRI检查序列包括快速自旋回波(TSE)T1WI、T2WI、短时反转恢复序列(STIR)。结果 36例PM、DM中31例大腿肌肉MRI上存在异常,异常表现包括肌肉炎性水肿30例、肌筋膜炎7例、皮下软组织水肿14例、肌肉萎缩伴脂肪浸润5例。8例治疗后复查MRI均显示炎性水肿较治疗前明显好转、吸收。结论 MRI检查是一种敏感、无创的检查手段,其在PM、DM诊断、疗效评估中有重要应用价值;肌肉和皮下组织炎性水肿是PM、DM患者最常见的肌肉MRI表现。
Objective： To investigate the magnetic resonance imaging （MRI） findings of muscles and to assess the utility of MRI in the diagnosis and monitoring of treatment response in patients with polymyositis （PM） and dermatomyositis （DM）. Materials and Methods： MR imagings were analysed retrospectively in 15 patients with PM and 21 patients with DM. MRI of thighs was performed for diagnostic purpose in all patients and during treatment the second MRI was underwent in 8 patients to monitor therapeutical effect. Fast spin echo Tl-weighted, T2-weighted and short tau inversion recovery （STIR） sequences of bilateral thighs were obtained in all patients. Results： Among 36 patients with PM/DM, changes were detected in 31 patients on MRI. The findings included muscule edema in 30 patients, inflammation in fascia in 7 patients, edema in the subcutaneous tissue in 14, muscule distrophy tbllowed fatty infiltration or replacement in 5. Inflammation absorbed partially or disappeared in all 8 patients who underwent MRI after treatment. Conclusion： MRI is a non-invasive, sensitive technique that is a powerful tool for diagnosis and monitoring of treatment response. Edema in muscle and subcutaneous tissue is the most common findings on MRI.
出处
《磁共振成像》
CAS
2012年第4期260-264,共5页
Chinese Journal of Magnetic Resonance Imaging
关键词
多发性肌炎
皮肌炎
磁共振成像
Polymyositis
Dermatomyositis
Magnetic resonance imaging
