摘要
目的探讨尼膜同联合3H治疗非动脉瘤性蛛网膜下腔出血后脑血管痉挛的机制及疗效。方法回顾性分析我院自2007年7月至2012年2月采用尼膜同联合3H治疗非动脉瘤性蛛网膜下腔出血患者73例,其中治疗组37例,给予尼膜同联合3H疗法,对照组36例,给予尼膜同治疗,采用临床疗效评定标准及出院时GOS评分,比较两组的疗效。结果治疗组的总有效率为81.08%,而对照组的总有效率为69.44%,治疗组的总有效率明显高于对照组,计数资料应用χ2检验,P<0.05,具有统计学意义。结论对于蛛网膜下腔出血Hunt-Hess分级Ⅲ级以上的患者,在常规应用尼膜地平的基础上,联合使用3H疗法,使蛛网膜下腔出血后血管痉挛得到较好的改善,预后比单纯使用尼膜地平效果佳。且对于非动脉瘤性SAH患者,3H疗法较为安全。
Objective To study the effect and mechanism of cerebral vasospasm of non-aneurysmal Subarachnoid Hemorrhage Vasospasm treated by Nimotop combined with 3H.Method A retrospective analysis on 73 cases of non-aneurysmal subarachnoid hemorrhage treated by Nimotop combined with 3H in our hospital from 2007July to 2012February,37 cases as treatment group,giving Nimotop combined with 3H therapy;36 cases as contrast group,giving Nimotop therapy.Comparing the clinical effects of two groups by the clinical curative effect evaluation and the GOS score when leaving hospital.Result The total efficiency of the treatment group was 81.08%,while the contrast group was 69.44%.The effective rate in the treatment group was significantly higher than that of the contrast group.Count data applied χ2 inspection,P0.05,having statistical significance.Conclusion For subarachnoid hemorrhage Hunt-Hess grade III patients,in the routine application of Nimotop basis,combining 3H therapy,the cerebral vascular spasm after subarachnoid hemorrhage gets preferable improvement,after cure effect better than simply using Nimotop.Further more,for the non-aneurysmal SAH patients,3H therapy is relatively safer.
出处
《中国医药指南》
2012年第22期60-61,共2页
Guide of China Medicine
