摘要
目的 :对自制盐酸地尔硫 艹卓 控释胶囊与进口缓释胶囊的释放度进行对比。方法 :用紫外分光光度法测定样品在胃、小肠及大肠 pH值环境下的释放度。 结果 :自制样品呈零级释放 ,进口样品呈一级释放。结论
OBJECTIVE:To compare the release rates of self made dilthiazem hydrochloride controlled release capsule prepared by the author with Herbesser 60 SR (Japan).METHODS:Release rate of the samples in different pH solution are measured by UV.RESULTS: Self made capsule satisfies the zero grade release,while the Herbesser 60 SR(Japan) satisfies the one grade release.CONCLUSION:The method to prepare the controlled release capsule developed by the author is feasible
出处
《华西药学杂志》
CAS
CSCD
北大核心
2000年第4期281-282,共2页
West China Journal of Pharmaceutical Sciences
关键词
盐酸地尔硫ZHUO
控释胶囊
释放度
Dilthiazem hydrochloride
Controlled release capsule
Release rate