摘要
目的:探讨复方樟柳碱(compound anisodine hydrobromide injection)治疗前部缺血性神经病变(anterior ischemic optic neuropathy,AION)的微视野的临床疗效。方法:AION患者66例107眼,采用患侧颞浅动脉旁皮下注射2mL,1次/d,10d一个疗程,基础疗程为四个,依照病情可增加1～2个疗程,观察眼底视盘形态与视功能改变,以反映其疗效的临床价值。结果:采用患侧颞浅动脉旁皮下注射四个疗程后,视力恢复有显著疗效者约55%,治疗第三、四疗程与第一、二疗程比较,视野缺损度改善有显著性差异(P<0.05),且患侧颞浅动脉旁皮下注射第四疗程视功能恢复最佳。结论:复方樟柳碱可以有效改善AION患者的视力和视野缺损度,是一种治疗AION方便、快捷、安全的方法。
AIM：To study the clinical effect of compound anisodine hydrobromide injection for the treatment of anterior ischemic optic neuropathy （AION） on microperimetry.METHODS：Totally 66 cases （107 eyes） with AION were treated by subcutaneous injection of the affected side next to the superficial temporal artery 2mL, 1 time/day, a course of 10 days. The basic courses were 4, according to the condition it can increase 2-3 courses. Fundus optic disc morphology and changes of visual function were observed in order to reflect the clinical value.RESULTS：Vision recovery had significant effect in 55% cases after subcutaneous injection of the affected side next to the superficial temporal artery for 4 courses. The 1st and 2nd courses compared with the 3rd and 4th courses, visual field defect degrees improved significantly（P0.05） and the visual function in the 4th course of subcutaneous injection of the affected side next to the superficial temporal artery recovered best.CONCLUSION：Compound anisodine hydrobromide injection can effectively improve the visual acuity and visual field defect degrees in AION patients, which is convenient, fast and safe.
出处
《国际眼科杂志》
CAS
2012年第9期1773-1774,共2页
International Eye Science
关键词
复方樟柳碱
前部缺血性神经病变
微视野
compound anisodine hydrobromide injection
anterior ischemic optic neuropathy
microperimetry
