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特应性皮炎患儿过敏原检测及分析 被引量:16

Allergy Screen and Analysis in Children with Atopic Dermatitis
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摘要 目的了解延边地区特应性皮炎患儿过敏原种类,为制定预防措施提供依据。方法采用免疫印迹法检测200例特应性皮炎患儿血清特异性IgE(sIgE)和IgE,并对朝鲜族和汉族患儿的检测结果进行比较。结果婴幼儿组59例(朝鲜族26例,汉族33例)和小儿组55例(朝鲜族28例,汉族27例)血清总IgE升高,婴幼儿组血清特异性IgE阳性53例(朝鲜族24例,汉族29例),小儿组有58例(朝鲜族30例,汉族28例),两年龄组间及两民族间差异均无统计学意义(P均>0.05)。两组患儿阳性率较高的过敏原依次为牛奶、牛肉和羊肉。结论延边地区婴幼儿组和小儿组特应性皮炎患儿血清总IgE水平和血清特异性IgE阳性率差异不显著,且朝鲜族和汉族患儿也无差异,特异性过敏原主要为牛奶、牛肉和羊肉。 Objective To investigate the allergen species in children with atopic dermatitis in Yanbian area so as to provide evidence for formulating the preventive strategies. Methods slgE and IgE of 200 cases of atopic dermatitis were assayed by immunoblotting. And the detection results of Korean and Han nationality were compared. Results The total serum IgE levels of the infant group ( Korean nationality 26 cases and Han na- tionality 33 cases) and the young children group ( Korean nationality 28 cases and Han nationality 27 cases) were increased significantly. Fifty-three cases of slgE in the infant group and 58 cases in young children group were increased. There were no significant difference in both age-group and nationality group (P 〉 0.05). The positive allergens were mainly milk, beef and mutton respectively. Conclusion There was no significant difference about the total IgE and sIgE between the infant and young children group, and the same about nationality group. The positive allergens are mainly milk, beef and mutton respectively.
出处 《中国皮肤性病学杂志》 CAS 北大核心 2012年第9期804-805,共2页 The Chinese Journal of Dermatovenereology
关键词 特应性皮炎 过敏原 特异性I_gE Atopic dermatitis Allergen Specific IgE
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