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联用碳酸锂治疗抑郁症降低其转躁率的系统评价 被引量:4

Meta--analysis of reduction of turning manic rate by lithium carbonate treatment in depression
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摘要 目的对已发表的关于联用碳酸锂治疗抑郁症并降低其转躁率的文献进行Meta分析。方法全面收集关于联用碳酸锂治疗抑郁症并降低其转躁率的对照研究资料,制定标准筛选纳入文献,对符合条件的研究结果用RevMan5.0软件进行Meta分析。结果共有8篇文献符合纳入标准,对其进行合并分析发现,联用碳酸锂治疗抑郁症可明显降低其转躁率(P〈O.00001)。结论碳酸锂可降低抗抑郁药物引起的转躁。 Objective Meta--analysis was performed to analyze comprehensively literatures on the treatment of depression with lithium carbonate. Methods Research reports on the treatment of depression with lithium carbonate were collected comprehensively and filtered according to the inclusion criteria, then analyzed with RevMan 5.0. Results After merging and analyzing the data only 8 reports were left. The data demonstrated that the turning of manic rate was much reduced by the treatment of depression with lithium earbonate(P〈0. 00001). Conclusions The treatment of depression with lithium carbonate reduced the turning manic rate.
出处 《神经疾病与精神卫生》 2012年第4期355-357,共3页 Journal of Neuroscience and Mental Health
关键词 碳酸锂 抑郁 转躁 Lithium carbonate Depression Turning manic
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