摘要
目的探讨血清、尿液中胱抑素C浓度在肾脏疾病中的诊断意义。方法选取正常体检者、确诊肾小球受损但肾小管未受损者、确诊肾小球与肾小管均受损者各31例,分别检测其血清和尿液中胱抑素C的浓度,并进行比较。结果与正常体检组比较:单独肾小球受损患者血清中的胱抑素C明显升高(P<0.05),但尿液中的胱抑素C并不升高,肾小球与肾小管均受损的患者血清、尿液中的胱抑素C均显著升高(P<0.05)。与单独肾小球受损者比较,肾小球肾小管均受损患者尿胱抑素显著升高(P<0.05)。结论同时检测血清、尿液中的胱抑素C浓度有利于及时判断肾小球、肾小管的受损程度。
Objective To explore the diagnostic significance of the serum and urine cystatin C con centration in renal disease. Methods The subjects with the normal physical examination results, those with the definite diagnosis of the injury to the glomeruli, but without the renal tubules involved and those with the injury to the glomeruli and renal tubules were selected ,31 cases in each one. The cystatin C concentration in the serum and urine was detected separately and made the comparison. Results Compared with the subjects with the normal physical examination results ,the cystatin C concentration was increased remarkably in the se rum for those with simple injury to the glomeruli （P 〈 0.05 ）, but the cystatin C concentration in the urine was not increased. For the subjects with the injury to the glomeruli and renal tubules, the cystatin C concentration was increased significantly in both the serum and the urine（ P 〈 0.05 ）. Compared with the subjects with the simple injury to the glomeruli, the cystatin C concentration was increased significantly for those with the injury to the glomeruli and renal tubules （P 〈 0.05 ）. Conclusion The detection of cystatin C concentration in the serum and urine is in favor of the timely judgment of the injury degree of the glomeruli and renal tubules.
出处
《世界中西医结合杂志》
2012年第8期692-693,共2页
World Journal of Integrated Traditional and Western Medicine
关键词
胱抑素C
肾小管
肾小球
Cystatin C
Renal Tubules
Glomeruli
