摘要
目的了解孕中期外阴阴道念珠菌病（VVC）治疗前后阴道pH值的变化，探讨阴道pH值与治疗效果的关系。方法选取60例孕14～28周阴道分泌物检查确诊为VVC感染者作为感染组，随机分为两组，每组30例，分别接受克霉唑阴道片和乳酸杆菌胶囊治疗，治疗前后测定阴道分泌物pH值，另选60例阴道分泌物正常的同孕龄孕妇为对照组。结果感染组阴道pH值4．14±0．12明显高于治疗组（3．83±0．08）及对照组（3．77±0．65）阴道pH值，F=212．99，P〈0．05，差异有统计学意义；克霉唑阴道片组（4．14±0．11）和乳酸杆菌组（4．15±0．12）治疗前阴道pH值均高于治疗后（3．77±0．06、3．89±0．05），t值分别为15．59和11．85，均P〈0．05，有统计学意义；克霉唑组治疗前后的阴道pH差值高于乳酸杆菌组，t=15．59，P〈0．05，两者有显著性差异。结论pH值可作为孕中期VVC辅助诊断指标，并对治疗效果有一定的预测作用。克霉唑阴道片治疗VVC效果优于乳酸杆菌。
Objective To investigate the relationship between vaginal pH value and curative effect by studying the changes of vaginal pH value before and after the treatment of vulvovaginal candidiasis （VVC）. Methods Sixty pregnant women with 14-28 gestational weeks who were diagnosed with VVC infection by checking vaginal secretion were selected as infection group, and they were randomly divided into two groups, one group treated with clotrimazole vaginal tablet （ n = 30） and the other group treated with lactobacillus capsule （ n = 30）. The vaginal pH values of them were determined before and after treatment. Another 60 pregnant women with same gestational age and with normal vaginal secretion were selected as control group. Results The vaginal pH value of VVC infection group （ 4. 14 ± 0. 12 ） was significantly higher than that after treatment （3.83 ±08） and that of control group （3.77 ±0.65） （F =212.99,P 〈0.05）, and the differences were statistically significant. The vaginal pH value of clotrimazole vaginal tablet group and lactobacillus capsule group before treatment （4.14 ±0.11, 4.15 ±0. 12） were higher than those after treatment （3.77 ±0.06, 3.89 ±0.05） （t value was 15.59 and 11.85, respectively, both P 〈 0.05 ）, and the differences were statistically significant. The difference in vaginal pH value before and after treatment in clotrimazole vaginal tablet group was greater than that in lactobacillus capsule group （t = 15.59, P 〈 0.05 ）, and there was significant difference. Conclusion Vaginal pH value can be an assistant diagnostic index of VVC in second trimester and is valuable in predicting curative effect. Clotrimazole vaginal tablet has better curative effect on VVC than lactobacillus capsule.
出处
《中国妇幼健康研究》
2012年第4期487-488,共2页
Chinese Journal of Woman and Child Health Research
关键词
妊娠
外阴阴道念珠菌病
阴道PH值
乳酸杆菌
克霉唑阴道片
pregnancy
vulvovaginal candidiasis （VVC）
vaginal pH value
lactobacillus
clotrimazole vaginal tablets
