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结核病流行趋势及治疗未来展望 被引量:26

Epidemiology and prospective therapy for tuberculosis
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摘要 结核病的治疗从最初的疗养疗法、人工气胸术和人工气腹疗法,到1944年链霉素的问世及化学治疗时代,再到1965年利福平的问世及短程化疗时代,以及今天的综合治疗时代及直接面视下的督导治疗。面对日益加剧的耐药结核病的流行趋势,结核病治疗的未来无疑应着眼于抗结核新药及药物新靶点的研究、结核病免疫治疗及治疗性疫苗的研究、结核病介入治疗的研究、结核病外科治疗的研究以及结核病中医药治疗的研究等。 Starting from sanatoria treatment, artificial pneumothorax and artificial pneumoperitoneum therapy, the treatment of tuberculosis has taken a stride in the development, thanks to the introduction of streptomycin and chemotherapy in 1944, subsequent advent of rifampicin and short-course chemotherapy as well as the current combination treatment and directly ob- served treatment. Confronting the challenges of increased prevalence of drug resistance, further therapy for tuberculosis will undoubtedly focus on the research of emerging anti-tuberculosis drugs and targets of drugs, immunotherapy, vaccines for therapeutic purposes, interventional treatment, surgery and traditional Chinese medicine.
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2012年第8期565-568,共4页 Chinese Journal of Practical Internal Medicine
关键词 结核病 药物疗法 免疫治疗 介入治疗 外科治疗 tuberculosis chemotherapy immunotherapy interventional therapy surgery
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