摘要
乳腺癌雌激素受体(ER)的测定已广泛应用于临床,资料证明乳腺癌组织内ER的含量与内分泌治疗的疗效有密切关系。近年来对乳腺癌ER水平与预后的关系也进行了许多观察和研究,存在着不同的意见。本文就185例乳腺癌组织ER测定的临床意义和对预后的影响分析如下。
Estrogen receptor (ER) had been studied by dextran-charcoal coated method in185 cases with primary breast cancer from 1979 to 1986. 127 patients (68.6%) had apositive ER assay (ER^+≥10 Fmol/mg protein). ER^+ rate was 90.9% in 11 stage 1 cases.69.0% in 113 stage 2 and 63.9% in 61 stage 3 patients. The ER^+ rate in cases withtumor less than 2 cm and larger than 5 cm were 80.0% and 65.9% respectively. Most ofpatients had received radical or extended radical mastectomy. The 5-year survival ratewas 78.2% for ER^+ and 64.5% for ER^- patients (P<0.05). The survival rate in casesover 50 years old was 81.1% in ER+ while 55.9% in ER^- (P<O.05). ER^+ patientswithout or with less than three lymph nodes metastasis had longer survival rate.
出处
《肿瘤》
CAS
CSCD
北大核心
1990年第1期16-18,共3页
Tumor
