摘要
目的探讨鲍曼不动杆菌感染的临床分布及药敏情况。方法对2009年1月-2011年12月的微生物送检标本进行统计分析,鲍曼不动杆菌2009年培养出19株,2010年29株(多重耐药菌株1株),2011年35株(多重耐药菌株2株),并对其分布的标本类型、科室及耐药情况进行分析。结果鲍曼不动杆菌在痰中检出率最高;科室分布依次为重症监护室(ICU)、神经外科、呼吸科;该菌对亚胺培南敏感性最高,对青霉素和头孢类抗生素耐药率均在55%以上。结论鲍曼不动杆菌感染患者的经验性抗生素治疗应根据其地区、医院最新的院内感染病原体分布及耐药性,合理选择抗生素;病情、高龄、免疫抑制剂、机械通气、多种侵入性操作及抗生素的使用为鲍曼不动杆菌医院感染危险因素;ICU存在多重耐药鲍曼不动杆菌的感染,应加以控制。
Objective To investigate the clinical distribution and drug sensitivity of Acinetobacter baumannii infection.Methods Microbial samples sent to our department for examination from January 2009 to December 2011 were statistically analyzed.Nineteen strains of Acinetobacter baumannii were cultured in 2009,29 in 2010（including 1 multi-drug-resistant strain）,and 35 in 2011（including 2 multi-drug-resistant strains）.The distribution of specimen type,departments and drug resistance was analyzed.Results The highest detection rate of Acinetobacter baumannii was found in sputum.Departments with high to low detection rate were respectively ICU,neurosurgery,and respiratory department.The bacteria was most sensitive to imipenem.The resistance rate to penicillin and cephalosporin were above 55%.Conclusions For patients with Acinetobacter baumannii infection,empiric antibiotics should be selected appropriately based on nosocomial infection distribution and drug resistance of pathogens in the local region and hospitals.The disease condition,old age,immunosuppressive agents,mechanical ventilation,a variety of invasive operations and antibiotic use are risk factors for nosocomial infection of Acinetobacter baumannii.ICU has the presence of multiple drug-resistant Acinetobacter baumannii infection,which should be controlled.
出处
《华西医学》
CAS
2012年第8期1218-1220,共3页
West China Medical Journal
关键词
鲍曼不动杆菌
感染
抗生素
耐药性
Acinetobacter baumannii
Infection
Antibiotics
Drug resistance
