摘要
目的:探讨多层螺旋CT(MSCT)在非小细胞肺癌放、化疗治疗过程中疗效价值的评估。方法:分析经病理证实的20例非小细胞肺癌在放、化疗治疗前后行MSCT灌注模式扫描,利用CT灌注软件对图像进行后处理,测定病变治疗前后的强化峰值(PEI)、对比剂达峰值时间(TTP)和血容量(BV)值,并经统计学处理,比较两者的差异。结果:非小细胞肺癌治疗前后的PEI、BV值差异有统计学意义(P<0.01),TTP值差异无统计学意义(P>0.05)。结论:CT灌注可以用于非小细胞肺癌放、化疗治疗过程中疗效价值的评估。
Purpose： To investigate the radio-chemotherapy response in patients with non-small cell lung cancer by using multisliee CT perfusion. Methods： Multislice CT perfusion mode scan were applied in 20 patients with non-small cell lung cancer（verified by pathology） before and after radio-chemotherapy. The images were processed by CT perfusion software. The peak enhancement image（PEI）, time to peak（TTP）, blood volume（BV） were measured before and after radio-chemotherapy. The data were compared by us- ing statistical analysis. Results： The PEI and BV values were with statistical significance between that before and after treatment in non-small cell lung cancer （P〈0.01）. The TTP value was with no statistical significance（P〉0.05）. Conclusion： CT perfusion can be used in the evaluation of radio-chemotherapy re- sponse in patients with non-small cell lung cancer.
出处
《中国医学计算机成像杂志》
CSCD
北大核心
2012年第4期303-306,共4页
Chinese Computed Medical Imaging
基金
上海市卫生局重点项目(2010016)
上海交通大学医学院院基金(09XJ22003)~~
