摘要
目的探讨超声B-flow血流成像（BFI）检查急性脑梗死患者颈动脉斑块的诊断价值，并与超声造影结果比较，评估其发现斑块内微小血流的能力。方法2008年9月至2011年9月，运用BFI对63例颈动脉斑块患者进行斑块内微小血流信号检测，其中急性脑梗死组48例，无症状对照组15例，将检测结果与症状及斑块回声进行相关分析，并根据超声造影增强特点分级后与BFI结果行对照研究。结果共发现184个斑块，急性脑梗死组140个斑块，对照组44个斑块。在急性脑梗死组，BFI在22个斑块内发现微小信号，阳性率为15．7％（22／140），而对照组仅在1个斑块内发现微小信号，阳性率为2．3％（1／44），差异有统计学意义（P=0．037）。BFI在超声造影分级I～Ⅳ级患者中发现微小血流信号的阳性率分别为4．8％（1／21）、2／18、8／17、4／7。BFI发现微小血流信号在Ⅲ级比率明显高于Ⅰ级和Ⅱ级，差异均有统计学意义（P=0．005，P=0．027），但Ⅲ级与Ⅳ级比较差异无统计学意义（P=1．000）。结论BFI能有效发现急性脑梗死患者颈动脉易损斑块内微小血流，且超声造影增强Ⅲ级、Ⅳ级的颈动脉斑块比Ⅰ、Ⅱ级更易被BFI检测出斑块内微小血流。
Objective To detect the micro flow signals of carotid plaque by ultrasound B-flow imaging （BFI） and elucidate its relationship with acute cerebral infarction. Methods A total of 63 patients with carotid plaques were divided into 2 groups, acute cerebral infarction （ ACI, n = 48 ） and control （n = 15 ）. BFI was used to detect the micro flow signals of plaques and comparisons were made with the categorizing results of contrast enhanced ultrasound （CEU）. The data were analyzed between two methods. Results The micro flow signals were detected in 15.7% （22/140）patients in the ACI group vs. 2. 3% （1/44） in the control group. There were more signals in hypoeehoic plaques. The detection percentage of micro flow in grade Ⅲ was significantly higher than that in grades Ⅰand Ⅱ with CEU （ P = 0. 005, P = 0. 027 ）. No significant differences existed between grades m and Ⅳ （ P = 1. 000 ）. Conclusion BFI can detect effectively the micro flow signals of carotid plaques and this characteristic is correlated with the symptoms of ACI.
出处
《中华全科医师杂志》
2012年第9期658-660,共3页
Chinese Journal of General Practitioners
关键词
超声检查
脑血管意外
动脉粥样硬化
Ultrasonography
Cerebrovascular accident
Atherosclerosis
