摘要
探讨早产儿极低体重儿与缺氧缺血性脑病患儿甲状腺激素的变化及临床意义。方法 :缺氧缺血性脑病 2 0例 ,早产儿 2 0例 ,正常足月儿对照 12例。用瑞士Serono公司发明的磁性均项酶标免疫技术测定FT3、FT4、TSH含量。结果 :缺氧缺血性脑病、早产儿组中血清FT3、FT4含量明显低于对照组 (P <0 .0 5 ) ,TSH与对照组比较无明显差异 (P >0 .0 5 )。结论 :缺氧缺血性脑病、早产儿血清FT3、FT4均显著低于对照组。提示缺氧缺血性脑病由于乏氧、酸中毒时甲状腺受损分泌功能低下 。
Objective:To study the clinical significance of the tryroid hormone in the hypoxic ischemic encephalopathy.Methods:HIE 20 cases,neonatal 20 cases,normal infants 12 cases.To test the amount of free triiodothyronine(FT3) and thyroxine (FT4) and thyroid stimulating hormone (TSH) with the technology of the enzyme immunoassay (Magnetic solid phase).Results:The FT3 and FT4 of HIE and premature was compared with normal control was lower (P<0.05),but the TSH was no difference (P>0.05).Conclusion:This study indicated that hypoxia and acidosis not only result in HIE,but also result in that thyroid gland injures and the thyroid hormone of secret is getting lower.As Premature grows not well in the uterus,the growth and function of thyroid gland are not mature.
出处
《中国优生与遗传杂志》
2000年第2期86-86,83,共2页
Chinese Journal of Birth Health & Heredity
关键词
缺氧缺血性脑病
早产儿
甲状腺素
测定
Hypoxic ischemic encephalopathy,Premature,Thyriod hormone
