摘要
目的探讨糖尿病患者24h尿白蛋白定量/肌酐(albumin/creatinine,A/C)比值与心脏功能的关系。方法根据90例糖尿病患者A/C比值将其分为正常组(43例)及异常组(47例)。应用多变量Logistic回归分析筛选糖尿病心功能异常的危险因素。筛选因素包括性别、年龄、体质量指数、血压、血脂、血糖、糖化血红蛋白及A/C比值。结果 A/C比值异常的糖尿病患者发生心脏收缩和舒张功能不全的比率较高(P<0.01)。多变量Logistic回归分析表明,A/C比值是糖尿病心脏收缩和舒张功能不全的独立预测指标(P<0.05),而性别、年龄、体质量指数、血压、血脂、血糖、糖化血红蛋白不是其预测指标(P>0.05)。结论 A/C比值与糖尿病患者心功能不全的发生有着密切的关系。A/C比值是糖尿病患者心脏功能异常的独立预测指标。
Objective To investigate the correlation of 24 - hour urine albumin/creatinine （ A/ C） ratio with cardiac function. Methods A total of 90 patients with diabetes mellitus （DM） were divided into normal group and abnormal group according to A/C ratio. Risk factors of abnormal cardiac function in diabetes were analyzed with multivariate Logistic regression analysis. Screening factors included age, sex, blood pressure, serum lipids, blood glucose, glycosylated hemoglobin （ HbAle） and A/C ratio. Results The incidence rate of cardiac insufficiency was higher in patients with abnormal urine A/C ratio （ P 〈 0.05 ）. Multivariate Logistic regression analysis showed that A/C ratio was an independent predictor of systolic and diastolic dysfunction in patients with DM （P 〈 0.05 ）. And the age, sex, body mass index （BMI） , blood pressure, serum lipids, blood glucose, HbAlc were not predictive indicators （ P 〉 0.05 ）. Conclusion A/C ratio has close relationship with heart dysfunction in patients with diabetes, and it is an independent indicator of cardiac function.
出处
《河北医科大学学报》
CAS
2012年第9期997-999,共3页
Journal of Hebei Medical University
关键词
糖尿病
白蛋白尿
心脏功能试验
diabetes mellitus
albuminuria
heart function tests
