摘要
合成了一种端基双键的芘衍生物荧光载体甲基丙烯酰胺基芘.基于光聚合反应将该荧光载体共聚固定于玻片表面,利用呋喃妥因对共价固定膜甲基丙烯酰胺基芘的猝灭作用,研制了一种测定呋喃妥因的荧光传感器.传感器避免了荧光载体的泄漏,具有较好的稳定性、重现性和选择性,使用寿命长.呋喃妥因测定的线性范围为8.0×10-7～1.0×10-4mol/L,检测限为6.0×10-7mol/L.将传感器用于水样中呋喃妥因的直接测定,回收率为96.0%～104.0%.
A pyrene derivative fluorescent carrier with a terminal double bond, methylacryloylam- idepyrene （MAAP） was synthesized. With the carrier molecules immobilized on the quartz slides via light copolymerization, a new fluorescent sensor was fabricated for the determination of nitrofurantoin based on the fluorescence quenching of MAAP. The quenching mechanism was discussed. The sensor exhibited ex- cellent stability, sufficient repeatability, good selectivity and long lifetime due to the prevention from leaching out of fluorescent carrier. The sensor showed linear responses toward nitrofurantoin in the con- centration range of 8.0×10-7-1.0×10-4mol/L with a detection limit of 6.0 × 10^ -7 mol/L. The recovery for the determination of nitrofurantoin in water samples ranged from 96.0% to 104.0%.
出处
《郑州大学学报（理学版）》
CAS
北大核心
2012年第2期76-80,共5页
Journal of Zhengzhou University:Natural Science Edition
基金
山西省自然科学基金资助项目
编号2009011015-2
关键词
甲基丙烯酰胺基芘
共价固定
荧光传感器
呋喃妥因
methylacryloylamidepyrene
covalently immobilized
fluorescent sensor
nitrofurantoin
