摘要
乙酰胆碱酯酶抑制剂可用于治疗阿尔茨海默病、运动失调、重症肌无力等多种神经系统疾病,按来源可分为化学合成和天然产物两大类,而天然产物是其重要来源。综述来源于植物、微生物及动物并具不同结构类型的乙酰胆碱酯酶抑制剂的研究进展。
Acetylcholinesterase inhibitors（AChEIs） are considered as a promising strategy for the treatment of neurological disorders, such as Alzheimer＇s disease, ataxia and myasthenia gravis. AChEIs could be usually classified as the synthetic and the natural products according to the different origins. The advances in AChEIs with different structures derived from plants, micro-organisms and animals were reviewed.
出处
《药学进展》
CAS
2012年第9期385-393,共9页
Progress in Pharmaceutical Sciences
基金
江苏省自然科学基金(No.BK2011622)
关键词
乙酰胆碱酯酶抑制剂
天然产物
抑制活性
acetylcholinesterase inhibitor
natural product
inhibitory activity
