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维、汉女性患者乳腺癌的分子分型及临床特征的比较分析 被引量:3

Comparative analysis of molecular subtypes and clinical features between Uyghur and Han patients with breast cancer
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摘要 目的比较维吾尔族(维族)与汉族乳腺癌患者分子分型及临床特征。方法回顾性分析2004年1月-2007年12月新疆医科大学第一附属医院收治的60例维族与176例汉族乳腺癌患者相关资料。对两民族乳腺癌患者的分子分型、组织学分型及临床分期构成比进行比较分析。结果维、汉族乳腺癌患者的分子分型和组织学分型分布无明显差异(P均>0.05);汉族患者的临床Ⅰ期多于维族患者(P<0.05),而维族患者的Ⅳ期多于汉族患者(P<0.05),维、汉族乳腺癌患者0、Ⅱ和Ⅲ期无明显差异(Ρ均>0.05)。结论维、汉族女性乳腺癌患者的分子分型构成无差异,但其临床特征有差异。 Objective To recognize the situations of molecular subtypes and clinical features between Uy ghur and Han ethnicity patients with breast cancer. Methods Retrospective ana the patients who were hospitalized in The First Affliated Hospital of Xinjiang M lysis edica clinical related data of 1 University from Jan- uary 2004 to December 2007. There were totally 236 patients, including 60 cases of Uyghur and 176 cases of Han. Compared the constituent ratio of molecular subtypes, histopathological types and clinical stage between the two groups. Results There was not statistically different between Uyghur and Han ethnicity patients with breast cancer in molecular subtypes and histopathological types (P 〉0.05); but there was statistically different in clinical stage (all P 〈 0.05), the patients of Han in clinical stage I were more than Uyghur 0.05). There group (P %0.05), however, Uyghur patients were more than Han in clinical stage Ⅳ (P % was not statlStlCa There is significant difference in lly cli different in clinical stage 0, Ⅱ and Ⅲ (all P 〉0.05). Conclusion nical features between Uyghur and Han patients with breast cancer, but the constituent ratio of molecular subtypes in the two groups are similar.
出处 《新疆医科大学学报》 CAS 2012年第9期1172-1174,共3页 Journal of Xinjiang Medical University
基金 新疆维吾尔自治区科技支疆计划项目(201291172)
关键词 乳腺癌 分子分型 临床特征 维吾尔族 汉族 breast cancer molecular subtype clinical feature Uyghur nationality Han nationality
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