期刊文献+

炎症与动脉粥样硬化及冠状动脉疾病的关系 被引量:7

Inflammatory responses in atherosclerosis and coronary artery disease
原文传递
导出
摘要 炎症在冠状动脉疾病和其他动脉粥样硬化性疾病中起着重要作用。在动脉粥样硬化早期病变处存在大量的免疫细胞,它们所分泌的一系列细胞因子加速病变的进程,激活炎症反应导致急性冠脉综合症的发生。动脉粥样硬化,是冠状动脉疾病的主要病因,是一种炎性疾病,炎症因子参与到免疫反应过程中,使得动脉壁处的病变得以发生、蔓延和活化。 Inflammation plays a key role in coronary artery disease(CAD) and other manifestations of atherosclerosis.Immune cells dominate early atherosclerotic lesions,their effector molecules accelerate progression of the lesions,and activation of inflammation can elicit acute coronary syndromes.Atherosclerosis,the main cause of CAD,is an inflammatory disease in which immune mechanisms interact with metabolic risk factors to initiate,propagate,and activate lesions in the arterial tree.
作者 王忠振 李芳
出处 《中国微生态学杂志》 CAS CSCD 2012年第9期862-864,F0003,共4页 Chinese Journal of Microecology
关键词 炎症 动脉粥样硬化 冠状动脉疾病 Inflammation Atherosclerosis Coronary artery disease
  • 相关文献

参考文献32

  • 1MURRAY C J, LOPEZ A D. Global mortality, disability, and the contri- bution of risk factors: Global Burden of Disease Study [ J ]. Lancet, 1997,349 (9063) : 1436-1442.
  • 2WILLIAM I Jr. The Pathology of atherosclerosis: plaque development and plaque responses to medical treatment[ J ]. Am J Med ,2009,122: 3-14.
  • 3PETER L,RIDKER P M,HANSSON G K,et al. In? ammation in ath- erosclerosis : from pathophysiology to practice [ J]. J Am Coil Cardiol, 2009,54(23) :2129-2138.
  • 4ROZENBERG I,SUSANNA H M S, MOCHARLA P, et al. Deletion of L-selectin increases atherosclerosis development in ApoE-/- mice[ J]. PLoS ONE,2011,6(7) :e21675.
  • 5DAI Guo-hao, KAAZEMPUR-MOFRAD M R, NATARAJAN S, et al. Distinct endothelial phenotypes evoked by arterial wavefons derived from atherosclerosis-susceptible and -resistant regions of human vascu- lature [ J]. PNAS ,2004,101 (41) : 14871-14876.
  • 6LANGER H F, BIGALKE B. Interaction of platelets and inflammatory endothelium in the development and progression of coronary artery dis- ease[J]. Seminars Thrombosis & Hemostasis,2010,36(2) :131-138.
  • 7LUNDBERG A M, HANSSON G K. Innate immune signals in athero- sclerosis[ J]. Clin Immuno1,2010,134( 1 ) :5-24.
  • 8HIMANSHU KUMAR,TARO KAWAI, SHIZUO AKIRA. Pathogen rec- ognition by the innate immune system [ J ]. Int Rev Immunol,2011,30 (1) :16-34.
  • 9FOKS A C, FRODERMANN V, BORG M, et al. Differential effects of regulatory T cells on the initiation and regression of atherosclerosis [ J ]. Atherosclerosis ,20 1 1,218 ( 1 ) : 53 60.
  • 10BRAUN N A, MENDEZ-FERNANDEZ Y V, COVARRUBIAS R, et al. Development of spontaneous anergy in invariant natural killer T cells in a mouse model of dyslipidemia[ J]. Arterioscler Thromb Vasc Biol,2010,30(1):1758-1765.

同被引文献73

  • 1金花.冠心病患者检测血胆红素和血脂的意义[J].中国误诊学杂志,2009,9(4):794-795. 被引量:2
  • 2章燕幸,陈怀红.血管内皮生长因子与动脉粥样硬化[J].国际脑血管病杂志,2006,14(6):452-455. 被引量:5
  • 3李国宏.冠心病患者胆红素、尿酸、血脂水平及其临床意义[J].临床和实验医学杂志,2010,9(6):425-426.
  • 4Mahmoud MS, Asmaa SA, Nahed AA.The reliability of the National Cholesterol Education Program's Adult Treatment Panel Ⅲ (NCEP/ATP Ⅲ)and the International Diabetes Federation (IDF) definitions in diagnosing metabolic syndrome (MetS) among Gaza Strip Palestinians[J]. Diabetes Metab Syndr, 2012, 6(1):4-8.
  • 5Sirdah MM, Abu Ghali AS, A1 Laham NA. The reliability of the National Cholesterol Education Program's Adult Treatment Panel I~ (NCEP/ATP Ill ) and the International Diabetes Federation (IDF) definitions in diagnosing metabolic syndrome (MetS) among Gaza Strip Palestinians[ J]. Diabetes Metab Syndr, 2012, 6(1) :4-8.
  • 6Jin Huang,Lei Qiu,Li Ding,Shaozhan Wang,Jing Wang,Quangang Zhu,Fengyu Song,Jinhong Hu.Ginsenoside Rb1 and paeoniflorin inhibit transient receptor potential vanilloid-1-activated IL-8 and PGE 2 production in a human keratinocyte cell line HaCaT[J]. International Immunopharmacology . 2010 (10)
  • 7Ji-Young Shim,Mi-Hyoung Kim,Hyung-Doo Kim,Ji-Yeon Ahn,Yeon-Sook Yun,Jie-Young Song.Protective action of the immunomodulator ginsan against carbon tetrachloride-induced liver injury via control of oxidative stress and the inflammatory response[J]. Toxicology and Applied Pharmacology . 2009 (3)
  • 8马岩岩.三七皂甙成分对脂多糖诱导巨噬细胞炎性因子的影响及其机制的研究[D].暨南大学2013
  • 9胡耿瑶.人参皂甙Rd通过影响多聚ADP-核糖保护脑缺血损伤的实验研究[D].第四军医大学2012
  • 10王乐乐.提取分离的人参皂苷Rg1对脂多糖诱导的小胶质细胞的炎症反应的影响[D].重庆医科大学2012

引证文献7

二级引证文献50

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部