摘要
目的探讨调节呼吸末正压通气（PEEP）水平对急性左心衰疗效及预后的影响。方法将49例急性左心衰患者随机分为2组,对照组（n=22）在常规药物治疗基础上加用低水平PEEP（〈5 cmH2O）,治疗组（n=27）在常规药物治疗基础上加用较高水平PEEP（5~10cmH2O）,记录2组治疗前、治疗后2 h及治疗后8 h的血压、心率、氧合指数（PaO2/FiO2）、二氧化碳分压（PaCO2）,观察疗效。结果 2组治疗后1 d及2 h血压、心率、PaO2/FiO2、PaCO2均较治疗前显著改善（P〈0.01）,治疗组各指标改善情况优于对照组（P〈0.05或P〈0.01）。结论较高水平的PEEP有利于急性左心衰的治疗。
Objective To explore the efficacy of positive end-expiratory pressure（PEEP） level on acute left heart failure（ALHF） and its influence on prognosis.Methods Forty-nine ALHF patients were randomly divided into two groups.The control group（n=22） received a low level of PEEP（〈5 cmH2O） in addition to a routine treatment,while the treatment group（n=27） received a high level of PEEP（5-10 cmH2O） in addition to a routine treatment.The blood pressure,heart rate,oxygen and index（PaO2/FiO2）,partial pressure of carbon dioxide（PaCO2） of the two groups before,2 h and 8 h after treatment were recorded to observe the clinical efficacy.Results The levels of blood pressure,heart rate,PaO2/FiO2 and PaCO2 in both two groups 1 d and 2 h after the treatment all improved（P〈0.01）.The improvements of indicators were better in the treatment group than in the control group（P〈0.05 or P〈0.01）.Conclusion Higher level of PEEP is effective in the treatment of ALHF.
出处
《实用临床医药杂志》
CAS
2012年第13期95-97,共3页
Journal of Clinical Medicine in Practice
关键词
心衰
呼气末正压
机械通气
heart failure
positive end-expiratory pressure（PEEP）
mechanical ventilation
