摘要
目的:观察盐酸文拉法辛胶囊治疗抑郁症的疗效及不良反应。方法:通过对全国7家精神病医院的262例抑郁症患者进行多中心,大样本,开放性的为期8周和26周的文拉法辛治疗观察。用汉密尔顿抑郁量表评定病情严重程度,通过减分率计算疗效和记录不良反应出现情况评价安全性。结果:本组在第8周末和第26周末基本痊愈率分别为:54.96%和65.65%,显效率分别为:33.59%和33.21%。不良反应轻微,无一例因药物反应导致治疗中断。结论:文拉法辛治疗抑郁症疗效确切,不良反应轻微,可作为一线抗抑郁药使用。
Objective:To research the efficacy and safety of Venlafaxine in the treatment of depression. Methods:262 cases were treated for 26 weeks. HAMD was used to measure the efficacy. Reduction rate was used to measure the Curative effect . Results : It was found that the basic recovery rate In 8 and 26 weeks is 54.96% and 65.65% , the effective rate In 8 and 26 weeks is 33.59% and 33.21% , Adverse reaction is slight. Conclusions: Venlafaxine show a satisfactory effect and safety in the treatment of depression.
出处
《中国民康医学》
2012年第17期2072-2073,共2页
Medical Journal of Chinese People’s Health