摘要
目的:观察单用利培酮和利培酮合用小剂量阿立哌唑治疗精神分裂症的疗效及不良反应。方法:将60例门诊女性患者按就诊先后顺序分成两组,对照组单用利培酮。治疗组服用利培酮的基础上加用小剂量阿立哌唑,并对两组的疗效及不良反应进行观察。结果:治疗12周后两组间疗效无显著差异,而治疗组的溢乳、月经失调、闭经、体重增加的表现明显少于对照组。结论:小剂量阿立哌唑能减少利培酮所致的溢乳、月经失调、闭经、体重增加等不良反应。
Objective：To observe the efficacy and side effects of risperidone and risperidone combined with low does of aripiprazole. Methods ：60 outpatients were divided into two groups by medical order, the treatment group was treated with risperidone combining with low deos of afiprprazole and the control group with fisperidone only. observe the efficacy and side offeets of two groups. Re- sults： there were no significant difference in efficacy in the 12th week; but the side effects of treatment group were significantly less than that of control group for example galaetorrhea ; menstrual disorder; amenorrhoea ; gain weight. Conclusions ： low does ariprprazole can reduce the rispefidone induced galaetorrhea ; menstrual disorder; amenorrhoea gain weight and so on.
出处
《中国民康医学》
2012年第17期2085-2086,共2页
Medical Journal of Chinese People’s Health
关键词
利培酮
阿立哌唑
疗效
不良反应
Risperidone
Aripiprazole
Efficacy
Side effects
