摘要
目的调查浙江省无偿献血者HIV感染的流行病学特征。方法对2008--2010年浙江省无偿献血人群血液筛查中发现的206例HIV感染献血者进行回顾性分析，获得这些感染者的人口学特征，利用SPSS16．0软件对这些数据进行统计分析。结果2008--2010年浙江省采供血机构献血者中HIV感染率分别为0．09％0（49／552585）、0．11‰（64／601639）和0．15‰（93／600893），平均感染率为0．12‰（206／1004063）。全省有5个地区的献血者HIV感染率在0．10‰以上，其中温州地区最高，为0．21‰。男性献血者HIV感染率为0．19‰，明显高于女性献血者的感染率0．02‰（X^2=96．21，P〈0．01）；〉25—35岁献血者HIV感染率0．19‰，为各年龄组最高（X^2=41．94，P〈0．01）；初中及以下学历献血者的感染率为0．21‰，明显高于高中及本科学历以上组（0．11‰和0．02‰，X^2=78．62，P〈0．01）。2008年初次献血者HIV感染率为0．12‰，高于再次献血者的0．05‰（X^2=7．26，P〈0．01），其余两年比较差异无统计学意义（X^2值分别为0．16和1．35，P〉0．05）。3年间街头献血感染率均高于非街头献血，差异有统计学意义（矿值分别为18．5、22．0和16．8，P〈0．01）。结论浙江省无偿献血人群中HIV感染率呈逐年增长态势，应加强对低学历青壮年男性等重点人群加强献血前的健康征询、筛查，确保血液安全。
Objective To investigate the epidemiologic features of HIV infections in voluntary blood donors in Zhejiang province. Methods A retrospective study was conducted in 206 cases of HIV-positive blood donors who were found from 2008 to 2010 by blood screening in Zhejiang Province, and the demographic data of those HIV carriers were analyzed using SPSS 16.0 software. Results The HIV-positive rates of voluntary blood donors in 2008, 2009 and 2010 were 0.09‰（49/552 585 ）, 0.11‰（64/601 639） and 0. 15‰（93/600 893） , respectively. There were five regions in Zhejiang province where HIV-positive rates exceeded 0. 10‰, and the highest one was 0.21‰ in Wenzhou. HIV infection rate of male blood donors was 0.19‰, which was higher than that of female donors （0.02‰, X^2 = 96.21, P 〈 0.01 ） ; donors with ages of 〉 25-35 had the highest infection rate （0. 19‰） among all age groups （X^2 = 41.94, P 〈 0. 01 ） ; blood donors with education of junior high school or lower had higher infection rate （0. 21‰） than those with education of senior high school and undergraduate or above （0. 11‰ and 0.02‰, X^2 = 78.62, P 〈 0. 01 ）. Infection rate of first-time blood donors in 2008 was 0. 12‰, higher than that of repeated donors （0. 05‰, X^2 = 7.26, P 〈 0. 01 ） ; while in 2009 and 2010, there was no difference between two groups （X^2 =0. 16 and 1.35, P 〉 0. 05）. Blood donors who used mobile donation sites had higher infection rate than those using institutional donation （X^2 = 18.5, 22. 0 and 16. 8 for 2008, 2009 and 2010, P 〈 0. 01 ）. Conclusions The risk of HIV infection is gradually increasing among voluntary blood donors in Zhejiang province. To ensure the blood safety, blood agencies should establish pre-donation health consultation for high-risk blood donors such as young men with low education.
出处
《中华临床感染病杂志》
CAS
2012年第3期158-161,共4页
Chinese Journal of Clinical Infectious Diseases
基金
卫生部科学研究基金省部共建项目（WKJ2011-2-017）
