摘要
目的探讨孕妇TORCH感染与流产、死胎、宫内感染、胎儿生长受限(FGR)、先天畸形等不良妊娠结局的相关性。方法采用酶联免疫吸附试验(ELISA)检测方法,对医院880例发生流产、死胎、宫内感染、胎儿生长受限、先天畸形等不良妊娠结局的孕妇进行血清TORCH-IgM抗体检测分析,并与同期正常的孕妇880例作对照。结果不良妊娠结局孕妇的TOX-IgM、RV-IgM、CMV-IgM和HSVⅡ-IgM阳性率分别为3.2%、4.2%、6.9%、5.1%,正常妊娠孕妇的TOX-IgM、RV-IgM、CMV-IgM和HSVⅡ-IgM阳性率分别为0.5%、1.3%、2.7%、1.6%,不良妊娠结局孕妇明显高于正常妊娠的孕妇,差异有统计学意义(P<0.01)。结论 TORCH感染与不良妊娠结局有极其重要的关系,TORCH-IgM检测对优生优育有着很重要的意义。
OBJECTIVE To investigate the correlation between TORCH infections in pregnant women and abnormal pregnancy outcomes including miscarriage,stillbirth,intrauterine infections,fetal growth restriction（FGR） and congenital malformations.METHODS By the means of enzyme-linked immunosorbent assay（ELISA）,the detection of serum TORCH-IgM antibody of 880 pregnant women with miscarriage,stillbirth,intrauterine infections,FGR or congenital malformations was performed,and during the same period 880 normal pregnant women were taken as control.RESULTS The positive rates of TOX-IgM,RV-IgM,CMV-IgM and HSV Ⅱ-IgM of the pregnant women with abnormal pregnancy outcomes were 3.2%,4.2%,6.9%,and 5.1%,respectively,while those of the normal pregnant women were 0.5%,1.3%,2.7%,and 1.6%,respectively,the positive rates of the pregnant women with abnormal pregnancy outcomes were significantly higher than those of the normal pregnant women,the differences were statistically significant（P〈0.01）.CONCLUSION TORCH infections are closely related to the abnormal pregnancy outcomes.Therefore,the detection of TORCH-IgM has great significance for the prenatal and postnatal care.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第17期3765-3767,共3页
Chinese Journal of Nosocomiology
关键词
TORCH感染
正常妊娠
不良妊娠结局
TORCH infections
Normal pregnancy
Abnormal pregnancy outcomes
